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1、课程名称:临床麻醉学教材名称:临床麻醉学授课时间: 授课对象:麻醉专业教学内容:全身麻醉期间严重并发症的防治计划学时:8学时重点:呼吸道梗阻的几种类型及其处理措施;呼吸抑制的原因及处理措施;低血压与高血压的产生原因及防止;引起心肌缺血的原因及防止;术中知晓及预防;苏醒延迟的原因及治疗难点: 心肌供血的生理知识、体温调节教学目的:掌握呼吸道梗阻、呼吸抑制、低血压与高血压、心肌缺血、术中知晓及苏醒延迟的原因和治疗;熟悉低温与体温升高的原因及处理,咳嗽、呃逆、术后呕吐、及恶性高热的原因及防治;了解心肌供血的生理知识,体温调节,术后肺感染的原因、表现及治疗教学方法:启发式教学、理论联系实际教具(挂图幻

2、灯投影及cai等):cai课件新内容新知识(注明来源及所占比例):心肌缺血的原因、诊断及处理,术中知晓的原因及预防,恶性高热的诱因、诊断及处理;气道高反应性策略。来源于anesthesia、占10%外语关键词:general anesthesia、complications、respiratory obstruction、regurgitation and aspiration、hypertension、hypotension、awarenss、myocardic ischemia、laryngospasm and bronchospasm、malignant hyperthermia、hyp

3、othermia参考资料:现代麻醉学第三版、anesthesia(miller第六版)、国外医学麻醉学分册、内科学课 堂 设 计:导课、介绍重点 10 设问、讲解舌后坠 10分泌物、脓痰、血液、异物阻塞气道 5 cai、讲解、举例反流与误吸 15 cai、讲解、举例插管位置异常、管腔阻塞、麻醉机故障 5 cai、讲解、举例气管受压 5 cai、讲解、举例口咽腔炎性病变、喉肿物、过敏性喉水肿 5 cai、讲解、举例喉痉挛 10 cai、讲解、举例支气管痉挛 10 cai、讲解、举例中枢及外周性呼吸抑制 15 cai、讲解、举例呼吸抑制的呼吸管理 10 cai、讲解、举例低血压的概念及原因 15

4、cai、讲解、举例低血压的预防 15 cai、讲解、举例低血压的措施 10 cai、讲解、高血压的原因、预防及措施 20 cai、讲解、举例心肌缺血的有关生理知识 15 cai、讲解、心肌缺血的诊断方法 5 cai、讲解、麻醉期间引起心肌缺血的原因及防治 20 cai、讲解、举例机体的产热、散热及体温调节 15 cai、讲解、低体温 20 cai、讲解、举例体温升高 15 cai、讲解、举例术中知晓 15 cai、讲解、举例苏醒延迟的原因 20 cai、讲解、举例苏醒延迟的治疗 15 cai、讲解、举例咳嗽 15 cai、讲解、举例呃逆 5 cai、讲解、举例术后呕吐 10 cai、讲解、举例

5、术后肺感染的原因及临床表现 20 cai、讲解、举例术后肺感染的诊断及治疗 15 cai、讲解、恶性高热的原因及临床表现 20 cai、讲解、举例恶性高热的治疗 10 cai、讲解、总结 5 板书教 学 过 程:chapter 14prevention and treatment of serious complications during general anesthesiaintroduction:complications of anesthesia involve three aspects:patient's condition;diathesis of anestheti

6、st;influence and fault of anesthetics、anesthetic apparatus and correlated instrument respiratory obstruction(呼吸道梗阻)一、glossocoma(舌后坠):最常见1aetiology(病因学):2liability factor(易患因素):justo major of corpus linguae(舌体过大)、short and stout(矮胖)、short neck(颈短)、lymphadenosis of throat posterior wal、hypertrophy of

7、tonsils(扁桃体肥大)3clinical features(表现): 4management(措施):side lying(侧卧)、head hypsokinesis(头后仰)、lift submaxilla(托下颌)、oropharyngeal and nasopharyngeal parichnos二、airway obstruction by secretion、purulent sputum、blood and foreign object1aetiology:inhalation of stimulant anesthetic,bronchiectasis(支气管扩张)、pul

8、monary abscess(肺脓肿)、pulmonary tuberculous cavity(肺结核空洞),operation of cavum nasopharyngeum(鼻咽腔)、oral cavity(口腔)、harelip(唇裂)手术,desquamation of tooth or artifcal teeth(牙或义齿脱落)2management:sufficient belladonna premedication(术前足量颠茄类药),intubation,suck respiratory tract,pull out dentium vacillatia or artif

9、cal teet三、regurgitation and aspiration(反流与误吸):mortality 50%75%1aetiology:anticholinergic agent(抗胆碱药)、morphine、general anaesthetics、muscle relaxant2clinical features:bronchospasm(支气管痉挛),tachypnea and dyspnea(呼吸急促、困难),moist rales(湿罗音),sever hypoxia(严重缺氧)3management:(1)fasting(禁食、水):adult:8h before ane

10、sthesiachildren:< 6m - milk and solid diet(4h),liquid(2h)636m - milk and solid diet(6h),liquid(3h)> 36m - milk and solid diet(8h),liquid(3h)(2)preoperative administration of an h2-receptor antagonist,such as cimetidine or ranitidine to decrease further secretion of additional acid.(3)applicati

11、on of gastric decompression by a wide-bore nasogastric tube; preparing for suction (4)full stomach/high level ileus:awake intubation whenever possible.(5)use of rapid - sequence induction and intubation without positive - pressure ventilation before intubation.(6)application of cricoid compression t

12、o control regurgitation of gastric contents.(7)extubation only when the patient is fully awake.(8)aspiration:head down position,suck vomitusbronchial antispasmodic and antibioticsrespiration supportlavage of trachea using 0.9%nacl四、malposition of catheter(插管位置异常)、ostruction of lumina(管腔堵塞)、anaesheti

13、c machine failure(麻醉机故障)1aetiology:catheter twist、block by sputum、corrugated tube twist、malfunction of respiration valve2management:examine position of catheter、respiratory sound,breathing circuit、respiration valve五、trachea compression(气管受压)1aetiology:tumour、mediastinum and edema calidum of neck or

14、mediastinum2management:六、inflamm affection of pharyngo-oral cavity(口咽腔炎症病变)、larynx tumer(喉肿物)、allergia laryngeal oedema(过敏性喉水肿)1aetiology:tumour、mediastinum and edema calidum of neck or mediastinum2management:七、laryngospasm and bronchospasm(喉痉挛与支气管痉挛):(一)laryngospasm:1aetiology:pharyngeal vagus nerv

15、e excitability(咽部迷走神经兴奋性)2evoked reasons:(1)hyoxemia、hypercapnia、secretion、oropharynx parichnos、laryngoscope、intubation(2)light anesthesia:3clinical features:4management:5prevention:avoid light anesthesia,avoid hypoxia and carbon dioxide accumulation(二)bronchospasm:1aetiology: (1)tracheal intubation

16、、aspiration、suck sputum(2)operation stimulate(3)thiopental sodium、morphine2clinical features:3management:respiratory depression一、central respiratory depression1aetiology:anesthetics、narcotic analgesics、hyperventilation、inflate lung unduly2management:(1)anesthetics reduce depth of anesthesia(2)narcot

17、ic analgesics naloxone(3)hyperventilation、inflate lung undulyvt二、peripheral respiratory depression1aetiology:muscle relaxant,hypopotassemia,general anaesthesia + epidural block2management:(1)muscle relaxantneostigmine bromide(2)hypopotassemiasupply potassium in time(3)spinal nerve blockwait三、respira

18、tion management1effective ventilation2select of ventilation mode:assistor respiration or controlled respirationhypotention and hypertension(低血压与高血压)一、hypotension1hypotension:> 20% or 80mmhg2aetiology:(1)anesthesia aspects:(2)operation aspects:(3)patient aspects:3prevention:(1)insufficient body fl

19、uidsufficiently supply(2)sever anaemia(3)sever mitral valve stenosis(4)myocardial ischemiamaintain blood pressure(5)myocardial infarction(6)congestive heart failure(7)°bbb、sick sinus syndromepacemaker(8)hypopotassemia(9)atrial fibrilation80120 bpm(10)using long-term corticosteroid4management:(1)reduce depth of anesthesia(2)transfusion,pro re nata ephedrine(3)sever coronary heart diseaseto support cardiac pump function(4)drag internal organssto

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