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Self-introductionOfDoctoralReexaminationCandidate：XXXXXApplying

Major：XXXXXXXXXXX11.Personalintroduction2.MasterResearch3.DoctoralResearchPlanCONTENTS21.Personalintroduction3Name:MaDongmeiDateofbirth:1998/09/09PoliticalAppearance:PartyMemberMajor:ComputermajorFaculty:SchoolofComputerandComputingGender:FemaleHometown:BeijingSchool:FudanUniversity1、Personalintroduction2.MasterResearch3.DoctoralResearchPlanEducationExperience41、Personalintroduction2.MasterResearch3.DoctoralResearchPlanEducationExperiencePeriodMajordegreeSchool2014.09-2020.07BiologicalEngineeringbachelordegreePekingUniversity2020.09-MicrobialandbiochemicalpharmacyMasterdegreePekingUniversity51、Personalintroduction2.MasterResearch3.DoctoralResearchPlanAwards2020NationalScholarshipforMaster'sStudents2021NationalScholarshipforPostgraduateStudentsOutstandinggraduatesofFudanUniversityin20222020NationalScholarshipforMaster'sStudents2021NationalScholarshipforPostgraduateStudentsOutstandinggraduatesofFudanUniversityin20222020NationalScholarshipforMaster'sStudents2021NationalScholarshipforPostgraduateStudents61、Personalintroduction2.MasterResearch3.DoctoralResearchPlan

PleaseaddtitlecontentTraditionalChineseMedicineBureauofGuangdongProvince(NO.20141065),NaturalScienceFoundationofGuangdongProvince(NO.2017A32217007)NationalUniversityStudentInnovationProgram72.MasterResearch81、Personalintroduction3.DoctoralResearchPlanMasterResearch2.MasterResearchPTBP1enhancesexon11askippinginMenapre-mRNAtopromotemigrationandinvasioninlungcarcinomacellsBackgroundObjectivesTechnologyMethodsResultsConclusions91、Personalintroduction3.DoctoralResearchPlanBackground2.MasterResearchSevenalternativesplicing(AS)subgroups:ExonSkippingAccountsForNearly40%OfASEvents;Alternative3′SpliceSite(3′SS)Selection(18.4%)And5′SSSelection(7.9%);IntronRetentionAccountsForLessThan5%;MutuallyExclusiveExons,AlternativePromoterUsage(3′utr)AndAlternativePolyadenylation(5′utr)AreNotFrequent.101、Personalintroduction3.DoctoralResearchPlanObjectives2.MasterResearchRegulatedbyPTBP1?TheexactmechanismmediatedMenaAShasnotbeenelucidated.ThepurposeofthisstudyistoexplorethemolecularmechanismofPTBP1inregulatingMenaalternativesplicingandroleofPTBP1inlungcarcinomacellsmetastasis.111、Personalintroduction3.DoctoralResearchPlanTechnologyMethods2.MasterResearchPleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontenthere121、Personalintroduction3.DoctoralResearchPlanResults2.MasterResearchPTBP1ishighlyexpressedinlungadenocarcinoma(LUAD)tissuesand95-DcellsandupregulationofPTBP1isassociatedwithEMTprogressPTBP1promotesmigrationandinvasionoflungcancercellsPTBP1enhancesexon11askippingofMenapre-mRNAinlungcancercellsPTBP1-mediatedmigrationandinvasionof95-DcellsarepartiallydependentonMenaINV133.DoctoralResearchPlan141、PersonalintroductionDoctoralResearchPlan2.MasterResearch3.DoctoralResearchPlanEarlygoalstudyhard,improveeveryday.studyhard,improveeverydayMedium-termGoalstudyhard,improveeveryday.studyhard,improveeverydaystudyhard,improveeveryday.studyhard,improveeverydayLateGoal151、PersonalintroductionDoctoralResearchPlan2.MasterResearch3.DoctoralResearchPlanEnterTextEnterTextEnterText

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EnterTextEnterText161、PersonalintroductionDoctoralResearchPlan2.MasterResearch3.DoctoralResearchPlan1、PleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentPleaseaddtitlecontenthere2、PleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentPleaseaddtitlecontenthere3、PleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentPleaseaddtitlecontenthere171、PersonalintroductionDoctoralResearchPlan2.MasterResearch3.DoctoralResearchPlanPleaseaddtitlecontenthere

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Pleaseaddtitlecontenthere18THANKYOUCandidate：XXXXXApplying

Major：XXXXXXXXXXX19Self-introductionOfDoctoralReexaminationCandidate：XXXXXApplying

Major：XXXXXXXXXXX1.Personalintroduction2.EducationExperience3.MasterResearch4.DoctoralResearchPlanCONTENTS1.Personalintroduction1、PersonalintroductionName:MaDongmeiDateofbirth:1998/09/09PoliticalAppearance:PartyMemberMajor:ComputermajorFaculty:SchoolofComputerandComputingGender:FemaleHometown:BeijingSchool:FudanUniversity2.EducationExperience2.1、EducationExperiencePeriodMajordegreeSchool2014.09-2020.07BiologicalEngineeringbachelordegreePekingUniversity2020.09-MicrobialandbiochemicalpharmacyMasterdegreePekingUniversity2.2、Awards2020NationalScholarshipforMaster'sStudents2021NationalScholarshipforPostgraduateStudentsOutstandinggraduatesofFudanUniversityin20222.3、EducationExperienceTraditionalChineseMedicineBureauofGuangdongProvince(NO.20141065),NaturalScienceFoundationofGuangdongProvince(NO.2017A32217007)NationalUniversityStudentInnovationProgram3.MasterResearch3、MasterResearchPTBP1enhancesexon11askippinginMenapre-mRNAtopromotemigrationandinvasioninlungcarcinomacellsBackgroundObjectivesTechnologyMethodsResultsConclusions3.1、BackgroundSevenalternativesplicing(AS)subgroups:ExonSkippingAccountsForNearly40%OfASEvents;Alternative3′SpliceSite(3′SS)Selection(18.4%)And5′SSSelection(7.9%);IntronRetentionAccountsForLessThan5%;MutuallyExclusiveExons,AlternativePromoterUsage(3′utr)AndAlternativePolyadenylation(5′utr)AreNotFrequent.3.2、ObjectivesRegulatedbyPTBP1?TheexactmechanismmediatedMenaAShasnotbeenelucidated.ThepurposeofthisstudyistoexplorethemolecularmechanismofPTBP1inregulatingMenaalternativesplicingandroleofPTBP1inlungcarcinomacellsmetastasis.3.3、TechnologyMethodsPleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontenthere3.4、ResultsPTBP1ishighlyexpressedinlungadenocarcinoma(LUAD)tissuesand95-DcellsandupregulationofPTBP1isassociatedwithEMTprogressPTBP1promotesmigrationandinvasionoflungcancercellsPTBP1enhancesexon11askippingofMenapre-mRNAinlungcancercellsPTBP1-mediatedmigrationandinvasionof95-DcellsarepartiallydependentonMenaINV4.DoctoralResearchPlan4、DoctoralResearchPlanEarlygoalstudyhard,improveeveryday.studyhard,improveeverydayMedium-termGoalstudyhard,improveeveryday.studyhard,improveeverydaystudyhard,improveeveryday.studyhard,improveeverydayLateGoal4、DoctoralResearchPlanEnterTextEnterTextEnterText

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