药学英语 标准试卷1

河北科技大学20

——20

学年第学期《专业英语》期末考试试卷标准答案考场号：座位号：学院：班级：姓名：学号：题号一二三四五六总分得分一、翻译（共20分,每题1分）。1

甲烷

2

乙醇3

丙酮4

碘5

缬氨酸

6

亮氨酸7

乙酸乙酯

8

酚9

酰胺

10

氯化钠11

Potassiumcarbonate

12

Toluene13

Alkane14

Potassium15

Cysteine

16

Methionine17

Sodiumbicarbonate18

Mercury19

Calciumcarbonate

20

Aromatics答案：1

Methane

2

Ethanol3

Acetone

4

Iodine5

Valine

6

Leucine7

Ethylacetate

8

Phenol9

Amide10

Sodiumchloride11

碳酸钾

12

甲苯13

烷烃

14

钾15

半胱氨酸

16

甲硫氨酸17

碳酸氢钠

18

汞19

CaCO3

20芳香化合物二、写出下列缩写的英文全称并翻译（共10分,每题2分）。1

DMF:2

MS:3

NMR:4

WTO:5

SFDA:答案：1

dimethylformamide

N,N-二甲基甲酰胺2

Massspectrometry

质谱3

NuclearMagneticResonanceSpectroscopy

核磁共振光谱4

WorldTradeOrganization

世界贸易组织5

StateFoodandDrugAdministration

（中国）食品药品监督管理局三、判断，并用×√表示（共16分,每题2分）。1

（）Drugdesignaimstoimprovethedesirableeffectsoftheleadcompoundandtoremovetheundesirableeffects.2

（）Arationaldesignbasedontheknowledgeofthemolecularcauseofthepathologicaldysfunctionisatypeofsearchfornewleadcompound.3

（）Analyticalchemistryisconcernedwiththechemicalcharacterizationofmatterandtheanswertotwoimportantquestions:whatisit(qualitative)andhowmuchisit(quantitative).4

（）Thuswereproduced,overmillionsofyears,theearthitselfandthechemicalelementsfoundontheearthtoday.5

（）Bybeingcognizantofthesepharmacologicprinciples,andbyremainingvigilanttocountlessinteractionbetweendrugandailingbody,onecansubstantiallyreducethesideeffectsofnumerousdrugs.6

（）Lowconcentrationsofsurfactantslowerthesurfacetensionandincreasetherateofdrugdissolution.7

（）Withnewcompounds,however,itispreferabletoconfirmtheidentificationthroughchemicaldegradationorbypreparingthecompoundbylaboratorysynthesis.8

（）Presently,asNMR,itisappliedinaverygeneralmannertosyntheticaswellastonaturalcompoundsinthesearchfornewleadcompound.答案:1

√

2

√

3

√

4

×

5

√

6

√

7

√

8

×四、单选题（共14分,每题2分）。1

Theleadcompoundisnotintendedtobeusedasaclinicalagent.ItisthestartingpointfromwhichaBusefulcompoundcanbedeveloped.A

naturally

B

clinicallyC

synthetically

D

pharmaceutically2

AnalyticalchemistryprovidestheBandtoolsneededforinsightintoourmaterialworldA

choices

B

methods

C

improvements

D

arrangements3

OnlyaboutBofthemorethan90naturallyoccurringchemicalelementsareessentialtolivingorganisms.A

20

B

30

C

40

D

504

SoliddrugproductsexemptedfromAincludetroches,tabletswhichareintendedtobechewed,anddrugproductsintendedforsustainedreleaseorprolongedorrepeataction.A

disintegrationtests

B

dissolutiontests

C

decompositiontests

D

deformationtests5

BulkflowintheDisveryrapid,asisdiffusionafterdrugshavetraversedmembranousbarriers,sotherate-limitstepindrugdistributionisusuallythepenetrationofthesebarriers.A

blood

B

bloodstream

C

bloodvessel

D

bloodstream6

BiochemicaltestsmayalsobeC:presenceofaglycosidecanbeconfirmedbyhydrolysiswithβ-glycosidase,ofamustardoilglycosidebyhydrolysiswithmyrosinaseandsoon.A

valuable

B

useful

C

invaluable

D

unuseful7

TherehavebeenseveralexampleswherethenaturalDforareceptorwasusedastheleadcompoundinordertodesignareceptorantagonist.A

target

B

structure

C

bioactivation

D

agonis答案:1

B

2

B

3

B

4

A

5

D

6

C

7

D五、英译汉（共20分,每题5分）。1

Thepresenttrendismassscreeningofhugelibrariescontainingseveralthousandmolecules.Thiswasmadepossiblebytheassociationofcombinationalchemistrywithhigh-throughputscreening.答案:目前的趋势是对包含有数千分子的巨大分子库进行筛选，高通筛选和组合化学的联合使其成为可能。2

Therearethreephasesintheanalysis:thefast-screeningphase,theidentificationphase,andpossiblequantification.答案:分析的过程分三个阶段进行：快速筛选阶段，确定阶段，可能的量化阶段。3

Analyticalchemistsworktoimprovethereliabilityofexistingtechniquestomeetthedemandsforbetterchemicalmeasurementswhichariseconstantlyinoursociety.答案:分析化学家的工作是改善现有技术的可靠性，以更好的化学检测方法满足我们社会不断的需求。4

Thetraceelementsrepresentaminisculefractionoftheweightofthehumanbody,butallessentialtolife,usuallybecausetheyareessentialtothefunctionofspecificproteins,includingenzymes.答案:微量元素的代表了人体重量的微乎其微的部分，但对生命很重要，通常是因为它们是必不可少的特殊蛋白质，包括酶的功能。六、问答题（共20分,每题5分）。1

Invitrodissolutiontesting,whatkindsoffactorsmustbeconsidered?答案:Foronething,thesizeandshapeofthedissolutionvesselmayaffecttherateandextentofdissolution.Asecondconsiderationistheamountofagitationandthenatureofthestirrer.Thetemperatureofthedissolutionmediummustalsobecontrolledandvariationsintemperaturemustbeavoided.Mostdissolutiontestsareperformedat37℃.Thenatureofthedissolutionmediumwillalsoaffectthedissolutiontest.2

Howtodefinepharmacokineticsandpharmacodynamics?答案:Byconvention,pharmacokineticsisdefinedasthestudyofthetime-courseofdrugabsorption,distribution,metabolismandexcretion,whereasthetermpharmacodynamicsreferstothecorrespondingpharmacologicalresponse.3

Whatisthesourcesoftheleadcompound?答案:Leadcompoundscanbeobtainedfromavarietyofdifferentsourcessuchasthefloraandfaunaofthenaturalworl