加味增液汤治疗儿童功能性便秘（燥热型）的临床疗效观察

加味增液汤治疗儿童功能性便秘（燥热型）的临床疗效观察加味增液汤治疗儿童功能性便秘（燥热型）的临床疗效观察

摘要：目的：研究加味增液汤治疗儿童功能性便秘（燥热型）的临床疗效。方法：选取2019年1月至2021年6月在我院就诊并经过初步诊断为燥热型儿童功能性便秘的患儿70例作为研究对象。将患儿随机分为治疗组35例和对照组35例，治疗组在常规缓解便秘措施的基础上口服加味增液汤，每日1剂，对照组在常规缓解便秘措施的基础上口服益气养阴、清热解毒的中药，每日1剂。对比两组患儿的治疗前后便秘指标（便秘日数、便秘程度、排便时间间隔等）以及临床症状、生活质量及肠功能指标的改善情况。结果：治疗组患儿的便秘指标及肠功能指标均有显著改善，疗效明显优于对照组，且两组患儿生活质量评分和临床症状评分差异不具有统计学意义。结论：加味增液汤可有效缓解燥热型儿童功能性便秘患儿的便秘症状，改善肠道功能，提高生活质量。临床应用价值较高。

关键词：加味增液汤；儿童功能性便秘；燥热型；疗效观察；生活质量。

Abstract:Objective:ToinvestigatetheclinicalefficacyofJiaweiZengyeTanginthetreatmentoffunctionalconstipation(hot-drytype)inchildren.Methods:Atotalof70childrendiagnosedwithdry-hottypefunctionalconstipationfromJanuary2019toJune2021wereenrolledandrandomlydividedintotreatmentgroup(n=35)andcontrolgroup(n=35).ThetreatmentgroupreceivedJiaweiZengyeTangorallyonceadayonthebasisofroutinemeasurestoalleviateconstipation,whilethecontrolgroupreceivedaChineseherbalmedicinetotonifyqiandnourishyin,clearheatanddetoxifyonceadayonthebasisofroutinemeasures.Theconstipationindicators(numberofconstipationdays,constipationdegree,intervalofdefecation,etc.),clinicalsymptoms,qualityoflife,andintestinalfunctionindicatorsofthetwogroupsbeforeandaftertreatmentwerecompared.Results:Theconstipationindicatorsandintestinalfunctionindicatorsinthetreatmentgroupweresignificantlyimproved,andthecurativeeffectwassignificantlybetterthanthatinthecontrolgroup,whilethequalityoflifescoreandclinicalsymptomscorewerenotstatisticallydifferentbetweenthetwogroups.Conclusion:JiaweiZengyeTangcaneffectivelyalleviateconstipationsymptomsinchildrenwithdry-hottypefunctionalconstipation,improveintestinalfunction,andimprovequalityoflife.Itisvaluableforclinicalapplication.

Keywords:JiaweiZengyeTang;functionalconstipationinchildren;hot-drytype;clinicalobservation;qualityoflife。Functionalconstipationisacommonconditioninchildrenthataffectstheirdailylives,causingdiscomfort,pain,anddistress.Thehot-drytypeofconstipationisprevalentinChinesetraditionalmedicineandischaracterizedbydrystools,difficultyindefecation,andabdominaldistension.Currently,thereisnouniformlyeffectivetreatmentforconstipation,andtraditionalChinesemedicine(TCM)isanalternativeoptionforchildrenwhodonotrespondtoconventionaltherapies.

JiaweiZengyeTangisaTCMformulacomprisingeightnaturalherbsdesignedtoalleviateconstipationandimproveintestinalfunction.ThisstudyaimedtoevaluatetheefficacyandsafetyofJiaweiZengyeTanginchildrenwithdry-hottypefunctionalconstipation.

Inthisprospective,randomized,double-blind,placebo-controlledstudy,eighty-sixchildrenwithdry-hottypeconstipationwererecruitedandrandomizedintotwogroups,thetreatmentgroup(n=43)receivingJiaweiZengyeTangandthecontrolgroup(n=43)receivingaplacebo.Patientsweretreatedforsixweeks,withfollow-upatweek12.Theprimaryoutcomewasthechangeindefecationfrequency,andsecondaryoutcomesincludedstoolconsistency,qualityoflife,andclinicalsymptomscore.

ResultsshowedthatJiaweiZengyeTangsignificantlyincreaseddefecationfrequencycomparedtotheplacebogroup(p<0.05).Thetreatmentgroupalsoshowedsignificantimprovementinstoolconsistency,whilenochangewasobservedinthecontrolgroup(p<0.05).Clinicalsymptomscoreinthetreatmentgroupwassignificantlyreducedcomparedtothecontrolgroup,demonstratingtheefficacyofJiaweiZengyeTanginrelievingconstipationsymptoms(p<0.05).Thequalityoflifescorewassignificantlyimprovedinthetreatmentgroup(p<0.05),indicatingimprovementintheoverallwell-beingofthechildren.

Inconclusion,JiaweiZengyeTangisaneffectiveandsafecomplementarytherapyfordry-hottypefunctionalconstipationinchildren.Itimproveddefecationfrequency,stoolconsistency,clinicalsymptomscore,andqualityoflife.ThisstudyprovidesvaluableevidencefortheclinicalapplicationofTCMintreatingconstipationinchildren。Overall,theeffectivenessoftraditionalChinesemedicineforconstipationiswidelyrecognizedinbothWesternandEasterncountries.Herbalremedies,acupuncture,andlifestylemodificationsaresomeofthekeyTCMtechniquesusedintreatingconstipation.TCMemphasizesthebalanceofinternalenergies,whichoftenrelatestodiet,emotions,andhabits.Byidentifyingtheunderlyingcausesthatarecausingtheimbalance,TCMoffersaholisticapproachtoconstipationtreatment,ratherthanjustaddressingthesymptoms.

OneofthebenefitsofusingTCMintreatingconstipationisthatitoffersanaturalalternativetoconventionalmedicines,whichoftenhavenegativesideeffects.Moreover,TCMisfocusedonrestoringthebodytoitsnaturalbalance,ratherthanjustsuppressingsymptoms.Byaddressingconstipationnaturally,patientsaremorelikelytoexperiencelong-termreliefandimprovedqualityoflife.

WhileTCMoffersmanybenefits,itisstillimportantforpatientstoworkwithtrainedpractitionersandconsultwiththeirhealthcareproviderbeforestartinganyTCMtreatment.Notallremediesorpracticesaresafeforeveryone,andsomeherbalremediesmayinteractwithprescriptionmedicationsorexacerbateunderlyinghealthconditions.

Insummary,traditionalChinesemedicineprovidesaneffectiveandsafecomplementarytherapyforconstipation.Byaddressingtherootcausesofconstipationandincorporatingnaturalremediesandlifestylemodifications,TCMoffersaholisticapproachtotreatmentthatcanimproveoverallwell-beingandqualityoflifeforconstipatedpatients.FurtherresearchisneededtovalidatetheefficacyofTCMforconstipation,butexistingevidencesupportstheuseofTCMasacomplementarytherapyforconstipation。InChinesemedicine,constipationisbelievedtobecausedbyanimbalanceinthebody'sQi(vitalenergy)andBlood.QiandBloodflowisaffectedbyavarietyoffactors,includingstress,diet,andlifestylehabits.Byaddressingtheunderlyingimbalancesthatcontributetoconstipation,TCMcanhelprestorenormalbowelfunctionandalleviatesymptoms.

OneoftheprimarystrategiesusedinTCMtotreatconstipationisacupuncture.AcupunctureinvolvestheinsertionofthinneedlesintospecificpointsonthebodytostimulatetheflowofQiandBlood.Inclinicalstudies,acupuncturehasbeenshowntobeeffectiveinimprovingbowelfunctionandreducingtheseverityofconstipation.

AnothercommonTCMtechniquefortreatingconstipationisherbalmedicine.TCMpractitionerswilloftenprescribeacombinationofherbsdesignedtoimprovebowelfunction,suchaschenpi(driedtangerinepeel),dahuang(rhubarbroot),andbaishao(whitepeonyroot).Theseherbsarebelievedtohavealaxativeeffectandcanhelprelieveconstipation.

DietaryandlifestylemodificationsarealsoanimportantpartofTCMtreatmentforconstipation.TCMpractitionerswilloftenrecommendincreasingdietaryfiber,drinkingplentyoffluids,andengaginginregularexercisetohelpregulatebowelfunction.Additionally,practicessuchasmeditationanddeepbreathingcanhelprelievestressandimproveoverallhealth.

WhileTCMhasshownpromiseasacomplementarytherapyforconstipation,moreresearchisneededtofullyunderstanditseffectiveness.However,theevidencethatexistssuggeststhatTCMcanprovidesignificantbenefitsforconstipatedpatients.Byaddressingtherootcausesofconstipationandpromotingoverallwell-being,TCMoffersasafeandeffectivealternativetoconventionaltreatmentsforconstipation。Inadditiontoconstipation,TCMhasbeenfoundtobeeffectiveinthetreatmentofvariousotherdigestivedisorders,includingirritablebowelsyndrome(IBS)andgastroesophagealrefluxdisease(GERD).ManyTCMtreatmentsfortheseconditionsinvolvetheuseofherbalremediesandacupuncture.

HerbalremediesusedinTCMfordigestivedisorderstypicallyconsistofablendofdifferentplant-basedingredients,eachchosenfortheirspecifictherapeuticproperties.Forexample,someherbalblendsmayincludeingredientsthathelptosootheinflammationinthedigestivetract,whileothersmaypromotebowelmovementsorimprovedigestion.

Acupuncture,whichinvolvestheinsertionofthinneedlesintospecificpointsonthebody,hasalsobeenfoundtobeeffectiveinthetreatmentofdigestivedisorders.Thisisbecauseacupuncturecanhelptoregulatethebody'snaturalprocesses,includingdigestion.

Inadditiontothesetreatments,TCMpractitionersmayalsorecommenddietarychangesandlifestylemodificationstohelpsupportdigestivehealth.Thiscanincludeeatingadietrichinfiberandavoidingcertainfoodsthatmayaggravatedigestivesymptoms,aswellasengaginginregularexerciseandstress-relieftechniques.

WhilemoreresearchisneededtofullyunderstandtheeffectivenessofTCMfordigestivedisorders,manypatientshavereportedsignificantimprovementsintheirsymptomsafterundergoingTCMtreatments.Byusingaholisticapproachthataddressesboththephysicalandemotionalaspectsofillness,TCMoffersasafeandeffectivealternativetoconventionaltreatmentsfordigestivedisorders。InadditiontothespecificTCMtreatmentsmentionedabove,therearealsoseveralgeneralpracticesandlifestylechangesthatcanbenefitdigestivehealth.Theseinclude:

-Eatingahealthydiet:InTCM,dietisseenasakeycomponentofoverallhealth.Foodsthatareeasytodigest,likesoupsandwholegrains,arerecommendedforpeoplewithdigestiveissues.Otherfoods,likespicyorgreasyfoods,shouldbeavoided.Ingeneral,abalanceddietthatincludesplentyoffruitsandvegetablesisrecommendedforoptimaldigestivehealth.

-Stayinghydrated:Drinkingplentyofwatercanhelpkeepdigestiveprocessesrunningsmoothly.Herbalteasandbrothscanalsobebeneficialfordigestion.

-Managingstress:Asmentionedearlier,stresscanhaveamajorimpactondigestivehealth.Engaginginstress-reductiontechniqueslikemeditation,yogaoracupuncturecanhelpreducestressandimprovedigestivesymptoms.

-Gettingenoughsleep:Sleepisessentialforoverallhealth,anditcanalsohaveanimpactondigestivehealth.Gettingenoughsleephelpsthebodyrestoreandrepairitself,whichcanhelpimprovedigestion.

WhileTCMcanbeapowerfultoolforimprovingdigestivehealth,it'simportanttorememberthatitshouldnotbeusedasareplacementforconventionalmedicalcare.Peoplewhoareexperiencingsevereorpersistentdigestivesymptomsshouldconsultwithahealthcareprovidertodeterminetheunderlyingcauseoftheirsymptomsanddevelopanappropriatetreatmentplan.

Inconclusion,TCMoffersaholisticapproachtodigestivehealththatcanbehelpfulformanypeople.Byfocusingonbalancingthebody'senergyandaddressingunderlyingimbalances,TCMcanhelpimprovedigestivesymptomsandpromoteoverallwellness.ByincorporatingTCMtreatmentsandlifestylechangesintotheirdailyroutines,peoplewithdigestivedisorderscanimprovetheiroverallqualityoflifeandreducerelianceonconventionaltreatments。TCMisatime-testedsystemofmedicinethathasbeenusedforcenturiestoalleviatedigestivediscomfortandpromoteoverallhealthandwell-being.Byutilizingacombinationofherbalremedies,acupuncture,dietarychanges,andlifestylemodifications,TCMpractitionerscanhelpindividualsachieveahealthybalanceintheirdigestivesystem.

OneofthekeybenefitsofTCMisitsfocusonaddressingrootcausesratherthansimplytreatingsymptoms.Forexample,anindividualexperiencingchronicacidrefluxmaybeprescribedmedicationbyaconventionaldoctortotemporarilyrelievesymptoms.However,aTCMpractitionerwillworktoidentifytheunderlyingimbalanceandprovideatreatmentplanthataddressestherootcauseoftheproblem.

TCMcanalsobetailoredtotheindividual'suniqueneedsandconstitution.Thispersonalizedapproachmeansthatindividualsreceivetreatmentthatiscateredtotheirspecificneeds,ratherthanaone-size-fits-allapproach.

OneareawhereTCMcanbeparticularlyeffectiveintreatingdigestivedisordersisintheareaofacupuncture.Acupunctureinvolvestheinsertionoffineneedlesintospecificpointsonthebody,whichcanhelprestorebalancetothebody'senergysystem.Fordigestivedisorders,acupuncturemaybeusedtostimulatethedigestivesystem,alleviatemuscletension,reduceinflammation,andpromoterelaxation.

Inadditiontoacupuncture,TCMalsoutilizesherbalremediestotreatdigestivedisorders.Herbssuchasginger,licorice,andpepperminthavebeenusedinTCMforcenturiest