生物制药技术名词

生物药专英语汇手生命科学学院2009年A

absolutelethaldose;LD100对致死剂量constant收速率常数testing加速试验acetylcholinesterase乙酰胆碱酯酶acetylcholine乙胆碱acrylicacidresin丙酸树酯activation激作用activator激剂preparation主靶向制剂acutetoxicitytest急毒性实验effect累效应加剂adenosine腺磷酸strength粘力粘性adhesives粘剂adjuvant佐肾腺素能神经receptor上腺素能受体adverse不反应气凝胶微粉硅of入粉雾剂aethylisoleas油乙酯聚物aggregation聚airsuspension空悬浮法albumin白白微球制剂生碱alkalosis;alkali-poisoning碱毒allergy;allergic变反应dateofqualityensuringmanufacturer药品负责期全式method相交替加入法lysate变细胞溶解物无型anaphylactic敏性药物反应anaphylatoxin敏毒素anatoxin;toxoid类素angleofrepose休止角拮作用antiadherent抗剂antibacterial菌谱antibody抗

抗原antioxidants氧剂对体防血清antitoxin抗素solubility现溶解度aprotinin抑酶芳族化合物waters芳水Arrhenius方程阿尼乌斯方程artificialantigen人工合成抗原artificial人免疫无菌操作法收药autoimmunity自免B杀活性杀菌作用bacteriophage噬体抑活性抑作用ballmill磨机base基吸附率基蜂弯力生利用度生利用度biochemicalapproach生学方法biochemistry物化学amine生胺生半衰期product生物制品生统计学物药剂学blood血液凝固bloodconcentration血药浓度blood血制品bloodexpander血量扩充剂barrier血屏障body体

bodyarea表面积water结水分breakage(Bk)脆碎度broad-spectrum广谱抗生素bulk密度、堆密度effect突效应C结饼毛管状capsules胶剂carcinogenictest致实验致物carrier载儿酚胺圆二色谱cellularimmunity胞免疫acetate(CA)酸纤维素chelatingagent螯剂chemical化分析chemicaldisinfection化消毒法chemical化物理学chemotherapy学药物治疗chewabletablets嚼片chiral手药物壳糖chlinicalpharmacy临药学cholinesterase胆酯酶时chronictoxicitytest;termtoxicity慢毒性实验时病学时辰药理学chronosusceptability时感受性时治疗prescription协处方Clausius-Clapeyron方程克劳修斯－克拉珀龙方程床药剂学pharmacology床药理学point对聚氧乙烯型非离子表活性剂CMC-Na羧甲基纤维素CMS-Na羧甲基淀粉钠聚coatedtablets包片

coatingmaterial表cocoabutter可豆脂coefficient扩系数酶cohesion凝性、粘着性cohesivestrength聚力compressionmethod汽法冷一匀化法冷结靶向胶囊剂成形性complement补系统complement补completeantigen完抗原complex复聚法complex助溶剂compliance顺性普片压度压性压力work压缩功concentration浓viscometer圆平板粘度计curve度曲线uniformity含量均匀度controllability可性controlledreleasepreparation控制剂controlledrelease控片controlled-release控制剂mixing流混合transport递透过coordination配位数表心物cosolvency潜cosolvent潜剂countermethod库特数法count个基准covalentbond价键外旋作用criticalrelative（）界相对湿度criticalvelocity临速度drugs;drugs天药物生

crushing粉crystalform晶crystalhabit晶、晶癖、结晶习性累分布excretion累积尿排泄曲线剪力(CYD)糊精cylinder圆栓体模型cytotoxic己醇细胞毒剂cytotoxicity胞素Ddecoction汤of圆度of球形度角层去脂质化desiccant;dryingagent燥剂detoxication解作用dextrin精dextrorotatoryform右体dextrose右糖dialysis渗析池法dicetyl磷二鲸蜡脂dielectric介常数scanningcalorimetry差扫描显热法thermalanalysis差热分析法diffusion扩扩混合胀流动diluents稀释剂、填充剂(silicones)二甲基硅油、硅油、硅酮pharmaceuticalpreparations定药物制剂discontinuous间灭菌法disinfection消崩剂解度diskmethod圆法dispensing调学dispersemedium分散介质disperse分散相dispersesystem分散体系dispersedphase分散相、相、非连续相dispersible分片

(DV)置换价dissolution;dissolving溶distilled蒸水DLVO论引力势能与斥力势能DME二醚DMSO二基矾form剂型doserate给方案或给药速度dose量concentration量或浓度的依存性interval给药间隔double-blindtechnique盲法dropdentifrices滴剂drugabsorption药吸收drug药物蓄积drugadministrationlaw药管理法drug药批号drugcarrier药载体drug合并用药drugdistribution物分布drug物消除drug药排泄druginteraction药相互作用drugmetablic药代谢酶drug药代谢drug物反应drugtest药试验DrugStandardMinistryHealthPeople's中人共和国卫生部药品标准drugstandard品质量标准drugtolerance耐性diseases源性疾病drug-loading载药量药时曲线drybulbtemperature干球温度dumping突释效应Eeardrops滴耳剂effectiveconcentration有浓度effectivehalt有效半期effectiverate有率effectiveness有性

RR效器效物effect效disintegrants泡崩解剂tablets泡片deformation弹变形recovery)弹性复原率work弹功elasticity性电质电electroporesis致孔法煎剂constant消速率常数emulsiferwatermethod水中乳化剂法、湿胶法emulsifierinmethod油乳化剂法、干胶法emulsions乳剂emulsion普通乳烯内内素enterictablets肠溶衣片entericcoating溶衣entericcontrolledtablets肠控释片enterohepatic肠循rate包率pharmacology环药理学epidermis表差异构作用solubility平溶解度water平水分essential必需氨基酸essentialdrugs基药物essentialfatty必脂肪酸ethical(prescription)处药人种药理学(EC)乙基维素etiological对治疗蒸料excitability兴奋性exotoxin外毒素expirydate;dateof药品有效期phase分介质、外相、连续相

extracts浸剂extravascularadministration血外给药滴剂眼膏剂Ffactorial析因设计fataldose致量fattyoils脂肪油fermentation发fillers填剂filmcoatedtablets薄衣片filmmethod薄散法film-coating薄衣films膜filteraid助剂filtration过firstpasseffectof肝过效应first-pass首效应fliudextracts流膏絮凝絮凝flow动曲线flowvelocity出速度流性mills流能磨、气流式粉碎机fluidity动性缓冲剂流化床包衣法water自由水分freelymovable自流动液体freezing;冷冻sizedistribution频率分布索状融G气分析体透过法GCP药临床试验管理规范gelatin甘胫胶糊gelatin明

acid-basecatalysis义酸碱催化日内瓦命名法geometricdiameter几学粒子geometric几异构细胞glidants助流剂GLP药物非临床研究管理规范gluconeogenesis糖生作用glycerins甘剂glyceryl硬脂酸、甘油酯glycolicacid羟乙酸glycolysis酵药生产质量管理规范density颗粒密度granules颗剂growthcurve生曲线客子Hhalfdose;medianlethaldose;数致死剂量half-life半衰期卤化物半原capsules硬囊剂hardness硬hemolysis溶血histamine组holonzymeandprosthetic酶与辅基hormone激host主子humidity湿度immunity体免疫stratumcorneum角层的水化作用水凝胶hydrolysis水（作用）hydrophile-lipophilebalance亲水亲油平衡值agent助剂助hydroxypropyl羟甲纤维素hygroscopicity吸性hyperreactivity高性皮注射用片

IIDDS植给药系统IEC离交换色谱法IEF等电点聚焦immobileliquid不流动液体immunoenhancement免增剂immunogenicity免原性inhibitor疫抑制剂mill冲击式粉碎机冲击力tablets植入片埋剂inclusion包物incompleteantigen不全抗原indirectcarcinogenesis间致癌differences;individualvariation个差异性industrial工业药剂学infusion液吸法注液in-liquiddrying液中干燥法（乳化－溶剂挥发法）innocuitymethod安试验法polycondensation界面缩聚法间体intoxication;poisoning中毒intra-arterial动脉内注射intracorporal药的体内过程皮注射intramuscular(IM)肌注射鞘注射intravascular血内给药(IV)route脉注射intrinsicdissolution特溶出速率inversetargeting反向靶向iontophoresis离渗法IR红光谱isoclectric等点聚焦异酶isoosmoticsolution等溶液isotonic等溶液isotope同素L

lagtime滞large大单室脂质体leastsignificant最小显著差数basis长基准levorotatory左体左糖lightquantum光子limitofusingaproduction药使用期LimulusAmebocyteassay内毒素试剂测定法limulustest鲎验法linear直相关搽剂liposome脂质体liquidmethod液浸法liquid无针液体注射器liquidparaffin液石碏toxicity长毒性实验liposomes长循环脂质testing长试验lotions洗剂lowdensitylipoprotein低度脂蛋白润滑剂溶酶M大子magneticreleasedosage磁控释制剂magneticpreparations磁药物制剂martin定向分径basis质基准matrix骨型maxialnoneffectiveEDO最无作用剂量maximalLDO最大耐受剂量maximumconcentration最大增溶浓度粒间机械镶嵌mediator;transmitter;质medical胶体溶液型药剂liquor酒剂熔融－匀化法wall表膜壁壳membrane-moderatedtypeTTS膜控释型mesomer内旋体

methylacrylate-methacrylateco甲基丙烯-烯酸甲酯胶乳micelle胶microcapsules表microemulsion微microencapsulation微包表术、微表化micromeritics粉学TTS贮库型microscropicmethod显微镜法microsomal微粒体微球microstreaming超束小有效量dose;MLD最致死剂量minitablet片合moistening润剂absorption吸性molconcentration尔分数浓度molarvolume;molevolume尔分子体积molarity摩浓度biology子生物学子囊disease子病pharmacology分子药理学solution分子溶液摩antibody单克隆抗体多能multilamellar多宝脂质体multilayertablets多层片process多离心法multipledoseadministration多量给药突Nnacentsoap生皂法纳囊nanoemulsion纳乳纳米脂质体纳球naonparticle纳粒滴鼻剂

antibody天抗体antigen天然抗原immunity天免疫神毒素newtonian牛顿粘度定律newtonianfluid牛流体脂质体，泡囊nitritepoisoning亚酸盐中毒非合水分非极化型肌松药acid非必需氨基酸nonionicsurfactant非离子表面活性剂囊泡fluid非顿流体nonprescriptiondrug非方nucleationtheory成核作用理论nucleotide核酸养素Oinserts用膜剂officialformula法定处方软剂低糖opiticalisomerization光异构口内药ORD旋色散design区设计渗透压OSSDDS口定位释药系统counter(OTC)处方药筛上分布Ppackingfraction充章涂涂剂锅包衣法paraffin石size粒分布partitioncoefficient(P)分配系perconcentration浓perhundred浓

perhundredconcentrationpphm度perconcentration浓被免疫preparation被动靶向制剂transport被动转运concentrationof药峰浓度drug药时间state钟状penetration透促进剂penetration皮吸收促进剂percentage百浓度吞噬作用药分析chemistry制化学制剂学equivalence药等效性制preparation药物制剂pharmaceutics药学淀微球药动力学药物遗传学pharmacokineticsmodel药动力学模型pharmacokinetics物动力学pharmacologicalavailability药利用度pharmacology药学phasecriticalpoint转相界点phaseseparation分离法（物理化学法）phasetemperature相转变湿度phasevolume相比超波法化降解physicaldependence身依赖性physical物药剂学pill滴剂安剂bindingratio血蛋白结合率血浆代用液血硬剂deformation塑变形塑粘度plastisity性polymerization聚

polymersin药高分子材料学polymorphism多晶型多polypeptide多porosity空率unit效单位效效强度injection无粉未注射器散powerful剧处前工作pregelatinized淀粉、预胶化淀粉、可性淀粉preparation剂prescription;recipe方preservative防腐sensitive压敏胶tape剥实celllayer棘一粒子prodrug前药物proenzyme酶激原prolongedpreparation长制剂抛射剂glycol二醇辅基伪态flow塑性流动精依赖性pulsed/pulsatile脉释药比瓶热Qquantumpharmacology子药理学假性流动Rraceme外消旋体racemization外旋化作用radiopharmaceutics放射药剂学

radiotoxicology放射毒理学raman拉randomfloc不则絮凝物of剪速度、切速率、速度梯度receptorantagonist体拮抗剂receptorstimulant受激动剂receptor感受器receptor受体直给药dosage相对给药间(RH)对湿度resistancedrugs抗性responsemethodology效应面优化法holagogue限制性剧药retardants阻滞剂osmosis反透流变学ribonucleicRNA核核酸rollingballtack滚试验RP-HPLC反高效液相色潽法研力safetycoefficient全系统safetyrange安全范围safety安性safflower藏花油saponins甙saturatedsolution饱溶液二粒子sedimentation沉法sedimentation沉容积比selectivity选性自式释药系统curveof药时半对曲线半成抗生素SEM扫电镜sensitivity敏性sensitization致试sensitization敏化作用sensitization致敏作用design序贯设计serum清

diameter有效径shape形状系数切混合shearing剪应力、剪切力、切力carcinogenictest短致癌实验effect副用sieving，筛分径sieving筛分法单聚法simplex单形优化法unilamellar小室脂质体sinkcondition漏skinadministration皮、粘膜表面给药slowpathway慢道软胶囊剂paraffin软蜡bridges粒间固体桥lipidnanospheres固体脂质纳米粒溶度参数溶度增solubilizer增剂溶solution溶片溶剂solvent;dissolvent溶solvent-nonsolvent溶－非溶剂法soybean-derived大甾醇acid-basecatalysis专属酸碱催化area地表面积法area地面积volume松比客鲸spirits醑海剂喷凝结法drying喷干燥法StatefoodandSFDA国食品药品管理局steadyconcentration稳血药浓度sterility无菌sterilization灭withdrawalsyndrome类醇停药综合征stickypowder粘粉体应缓和

影因素试验、强化试验stripingcorneum去角质层poisoning亚性毒subcutaneousroute下注射sublingualtablets舌片纳米乳sugartablets糖片supercriticalFluid超临