rel-α-Vitamin-E-rel-plus-α-Tocopherol-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemErel-Vitamin ECat. No.: HY-N0683ACAS No.: 2074-53-5Synonyms: rel-(+)-Tocopherol; rel-D-Tocopherol分式: CHO分量: 430.71作靶点: Others作通路: Others储存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 60 m

2、g/mL (139.30 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.3217 mL 11.6087 mL 23.2175 mL5 mM 0.4643 mL 2.3217 mL 4.6435 mL10 mM 0.2322 mL 1.1609 mL 2.3217 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 rel-Vitamin E (rel-(+)-Tocopherol)种具有抗氧化特性的维素，也种混

3、合物。体外研究Vitamin E is a lipid-soluble, chain-breaking type of antioxidant present in human blood. Vitamin E works as afree radical scavenger and has the primary function of destroying peroxyl radicals. Thus, it protects long-chain polyunsaturated fatty acids (e.g., cell membranes or low-density lipopr

4、otein cholesterol) from oxidationor destruction. Its association with vitamin C is of great pathophysiological importance, because inhibition of1/2 Master of Small Molecules 您边的抑制剂师www.MedChemElipid peroxidation by -tocopherol occurs through its conversion into an oxidized -tocopheroxyl radical,whic

5、h in turn is regenerated to -tocopherol through reduction by redox-active reagents 1.-Tocopherol can inhibit the recruitment of lymphocytes and eosinophils 1.体内研究 In order to longitudinally relate vitamin E status, evaluated by means of - and -tocopherol measured inerythrocytes membranes, to inflamm

6、atory state and oxidative stress by means of total antioxidant capacity ofplasma and lipid peroxidation biomarkers, and to assess its association to hard long-term outcomes (e.g.,overall and cause-specific graft and recipient loss), and to be able to likewise account for liver, lung, andheart transplant recipients 1.REFERENCES1. Sotomayor CG, et al. Plasma versus Erythrocyte Vitamin E in Renal Transplant Recipients, and Duality of Tocopherol Species.Nutrients. 2019 Nov 19;11(11). pii: E2821.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use on