S-MCPG-plus-MCPG-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE(S)-MCPGCat. No.: HY-100406CAS No.: 150145-89-4Synonyms: (+)-MCPG分式: CHNO分量: 209.2作靶点: mGluR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 6.2 mg/mL

2、(29.64 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 4.7801 mL 23.9006 mL 47.8011 mL5 mM 0.9560 mL 4.7801 mL 9.5602 mL10 mM 0.4780 mL 2.3901 mL 4.7801 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 (S)-MCPG(RS)-MCPG的同分异构体，选择性的 group I/group

3、II metabotropic氨酸受体拮抗剂。REFERENCES1. Bordi F et al. Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemENeuropharmacology. 1996;35(11):1557-65.2. Sekiyama N et al. Structure-activity relationships of

4、new agonists and antagonists of different metabotropic glutamate receptor subtypes.Br J Pharmacol. 1996 Apr;117(7):1493-503.3. Jane DE et al. Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects inneonatal rat motoneurones and rat thalamic neurones. Neuropharmacology. 1993 Jul;32(7):725-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax