Sertaconazole-nitrate-FI7056-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESertaconazole nitrateCat. No.: HY-B0736ACAS No.: 99592-39-9Synonyms: FI7056分式: CHClNOS分量: 500.78作靶点: Fungal作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (199.

2、69 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.9969 mL 9.9844 mL 19.9688 mL5 mM 0.3994 mL 1.9969 mL 3.9938 mL10 mM 0.1997 mL 0.9984 mL 1.9969 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，

3、体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (4.99 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (4.99 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂

4、师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (4.99 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Sertaconazole硝酸盐局部谱的抗真 剂，可作于表和粘膜的感染。REFERENCES1. Liebel, F., et al., Anti-inflammatory and anti-itch activity of sertaconazole nitrate. Arch Dermatol Res, 2006. 298(4): p. 191-9.2. P

5、faller, M.A. and D.A. Sutton, Review of in vitro activity of sertaconazole nitrate in the treatment of superficial fungal infections. DiagnMicrobiol Infect Dis, 2006. 56(2): p. 147-52.3. Sur, R., et al., Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway. J InvestDermatol, 2008. 128(2): p. 336-44.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;