Luteolin-Luteolol-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELuteolinCat. No.: HY-N0162CAS No.: 491-70-3Synonyms: Luteolol; Digitoflavone; Luteoline分式: CHO分量: 286.24作靶点: Autophagy; Mitophagy作通路: Autophagy储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO

2、: 100 mg/mL (349.36 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.4936 mL 17.4679 mL 34.9357 mL5 mM 0.6987 mL 3.4936 mL 6.9871 mL10 mM 0.3494 mL 1.7468 mL 3.4936 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再

3、依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (8.73 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (8.73 mM); Clear solution1/2 Master of S

4、mall Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Luteolin (Luteolol)种天然 酮类化合物，在抗癌 具有常重要的潜能。户使本产品发表的科研献 Front Pharmacol. 2018 Jun 13;9:620.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Liping Ma, et al. Luteolin exerts an anticancer effect on NCI-H460 human non-small c

5、ell lung cancer cells through the induction of Sirt1-mediated apoptosis. Molecular MedicineReports, 2015, 12 (3): 4196-42022. Su Bog Yee, et al. Growth inhibition of luteolin on HepG2 cells is induced via p53 and Fas/Fas-ligand besides the TGF- pathway.International Journal of Oncology, 2015, 47 (2)

6、: 747-7543. Pang Tao, et al. Effect of Luteolin on the Improvement of Cancerous Cachexia in Model Mice. China Pharmacy, 2015-074. Divyashree Ravishankar, et al. Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of MedicinalChemistryVolume 97, 5 June 2015, Pages 259274McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 40