Diphenmanil-methylsulfate-Diphemanil-mesylate-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDiphenmanil methylsulfateCat. No.: HY-16171CAS No.: 62-97-5Synonyms: Diphemanil mesylate分式: CHNOS分量: 389.51作靶点: mAChR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解

2、性数据体外实验 : 16.67 mg/mL (42.80 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.5673 mL 12.8366 mL 25.6733 mL5 mM 0.5135 mL 2.5673 mL 5.1347 mL10 mM 0.2567 mL 1.2837 mL 2.5673 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Diphemanil硫酸甲酯能结合毒蕈碱型酰胆碱受体进降低胃酸，唾

3、液和汗液的分泌排泄。REFERENCES1. Kng M, Diamond L. Effect of inhaled diphemanil methylsulfate, a parasympatholytic agent, on histamine induced bronchoconstriction in1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEasymptomatic asthmatics. Ann Allergy. 1984 Jan;52(1):22-5.2. Vidal AM, Rey E, Pons G et al. Phar

4、macokinetics of diphemanil methylsulphate in healthy subjects. Eur J Clin Pharmacol.1992;42(6):689-91.3. Vidal AM, Chron G, Rey E et al. Pharmacokinetics of diphemanil methylsulphate in infants. Eur J Clin Pharmacol. 1993;45(1):89-91.4. Chron G, Vidal AM, Rey E et al. Pharmacokinetics of diphemanil

5、methylsulfate in infants. Arch Pediatr. 1994 Jan;1(1):33-7.5. Adamantidis M, Dumotier B, Caron J, Dupuis B. Electrophysiologic effects and arrhythmogenic potential of diphemanil methylsulfate onrabbit purkinje fibers. Correlations with clinical observations of QT prolongation in pediatrics. Arch Mal Coeur Vaiss. 1998 Dec;91(12):1487-94.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 0