生物科技之新知與常識-醫藥及保健食品ppt课件

1、張 正 傑出人才講座教授國 立 交 通 大 學生物科技學系暨研讨所 : changca.tw國立交通大學生物科技系所生物科技之新知與常識-醫藥及保健食品.張 正學歷國立台灣大學化學系學士美國匹茲堡大學生物無機及分析化學博士經歷美國麻省理工學院化學系訪問學者美國衛斯理女子學院(Wellesley College)化學系助理教授美國德州大學化學系終生職副教授美國鋁業公司(Aluminum Co. of America) 生物科技研讨組長 美國必治妥施貴寶藥廠(Bristol-Myers Squibb)診斷藥劑研讨組長 美國Nycomed Salutar生物科技公司研發副總裁美國Frost & Su

2、llivan醫藥情報公司醫藥及生物科技情報部主任美國國家衛生研讨院 (National Institutes of Health)無機生物研讨小組(Metallobiochemistry Study Section)委員美國化學會Bioconjugate Chemistry期刊編審委員 台灣國立交通大學生物科技研讨所籌備主任、教授兼創所所長經濟部、原能會、工研院等政府部會、財團法人、私人公司顧問國立交通大學生物科技系所.生物科技之新知與常識新知：學術之新發現，偶而有問題Cold fusion(低溫核鎔合，1989)，恐龍基因(1995)，複製幹細胞(2006) 常識：新知或經驗經過長期實踐而被

3、社會大眾共同接受，常以訛傳訛感冒怎麼辦？該喝甚麼水？有機食品？如何分辨日用產品之真偽及好壞？國立交通大學生物科技系所Bora Bora.Cold Fusion Ambient temperature fusion technologies and developmentsCold fusion(低溫核鎔合，1989)Scientific consenses An current agreement, not scienceSalt Lake Tribune Mar. 23, 2004 Cold fusion frozen in time - Physicists and chemists de

4、voured newspaper accounts and pored over TV clips for clues about what Stanley Pons and Martin Fleischmann were doing. Graduate students stayed up all night tweaking laboratory equipment in hopes of glimpsing cold fusion.國立交通大學生物科技系所.恐龍基因 - 陳章良與王小目前网上对陈章良的指摘主要有四点： 一、陈章良抄袭。 二、陈章良伪造恐龙蛋基因研讨。 三、陈章良生活作风有

5、问题。 四、陈章良学术成果太少。 國立交通大學生物科技系所.複製幹細胞(2006) Science, 303, 1669, 2004 (retracted on Jan. 12, 2006)Evidence of a Pluripotent HumanEmbryonic Stem Cell LineDerived from a Cloned BlastocystWoo Suk Hwang,* Young June Ryu, Jong Hyuk Park,Somatic cell nuclear transfer (SCNT) technology has recently been used

6、to generate animals with a common genetic composition. In this study, we report the derivation of a pluripotent embryonic stem (ES) cell line (SCNT-hES-1) from a cloned human blastocyst. The SCNT-hES-1 cells displayed typical ES cell morphology and cell surface markers and were capable of differenti

7、ating into embryoid bodies in vitro and of forming teratomas in vivo containing cell derivatives from all three embryonic germ layers in severe combined immunodeficient mice. After continuous proliferation for more than 70 passages, SCNT-hES-1 cells maintained normal karyotypes and were genetically

8、identical to the somatic nuclear donor cells. Although we cannot completely exclude the possibility that the cells had a parthenogenetic origin, imprinting analyses support a SCNT origin of the derived human ES cells. 國立交通大學生物科技系所.複製幹細胞(2006) Science, 308, 1777, 2005 (retracted on Jan. 12, 2006)Pati

9、ent-Specific EmbryonicStem Cells Derived fromHuman SCNT BlastocystsWoo Suk Hwang,* Sung Il Roh,3 Byeong Chun Lee,1Patient-specific, immune-matched human embryonic stem cells (hESCs) are anticipated to be of great biomedical importance for studies of disease and development and to advance clinical de

10、liberations regarding stem cell transplantation. Eleven hESC lines were established by somatic cell nuclear transfer (SCNT) of skin cells from patients with disease or injury into donated oocytes. These lines, nuclear transfer (NT)hESCs, grown on human feeders from the same NT donor or from genetically unrelated individuals, were established at high rates, regardless of NT donor sex or age. 國立交通大學生物科技系所.前韓國首爾大學教授 黃禹錫國立交通大學生物科技系所.生物科技相關資訊來源 讓數字說話 战略與預測原始資料(Primary) : 國內外各原始資訊彙整次級資料(Secondary) : 轉載資料網路、人脈、文獻、媒體產- 公司年報、新聞發布、市場情報、證券公司官- 官方會議記