USP色谱柱分类

1、L1和L8是美国药典（USP）规定的色谱柱编号，其实就是ODS柱和NH2柱。下面是USP规定的编号所对应的色谱柱类型。L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：3050mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：3050mm表面多孔薄壳型硅胶柱L5：3050mm表面多孔薄壳型氧化铝柱L6：3050mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10

2、:多孔硅胶微球键合氰基固定相（CN）,简称CN柱L11:键合苯基多孔硅胶微球固定相，简称苯基柱L12:无孔微球键合季胺功能团的强阴离子交换柱L13:三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15:已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17:氢型磺化交联苯乙烯-二乙烯基苯共聚物，强阳离子交换柱L18：310mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯一二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多

3、孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯一二乙烯基苯共聚物微球填料柱L22:带有磺酸基团的多孔苯乙烯阳离子交换柱L23:带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。能分离分子量1005000MW范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：3050mm的全多孔硅胶微粒L28：多功能载体，100A的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:氧化铝，反相键合

4、，含碳量低，氧化铝基聚丁二稀小球,5mm，孔径80AL30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000A的交联苯乙烯和二乙烯基苯（55%）强阴离子交换树脂L32:L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量400040000MW范围蛋白质分子的球形硅胶固定相,pH稳定性好L34：铅型磺化交联苯乙烯一二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150AL36:5mm胺丙基硅胶键合L-苯基氨基乙酸一3,5二硝基苯甲酰L37：适合分离分子量200040000MW的聚甲基丙烯酸酯凝

5、胶L38:水溶性甲基丙烯酸酯基质SEC色谱柱L39:亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris3,5一二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定al酸糖蛋白固定相L42:C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60A高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45:卩-环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1Octadecylsilanechemicallybondedtoporoussilicaorceramic.L1十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，

6、3-10u。L2Octadecylsilanechemicallybondedtosilicagelofacontrolledsurfaceporositythathasbeenbondedtoasolidsphericalcore,30to50口mindiameter.L2十八烷基键合硅烷化学键合于表面空隙率一定的键合在紧密球核上的硅胶，粒径30-50u。L3Poroussilicaparticles,5to10口mindiameter.L3多孔硅胶颗粒，粒径5-10u。L4Silicagelofcontrolledsurfaceporositybondedtoasolidspherical

7、core,30to50口mindiameter.L4表面空隙率一定的硅胶键合于紧密球核上，粒径30-50u。L5Aluminaofcontrolledsurfaceporositybondedtoasolidsphericalcore,30to50口mindiameter.L5表面空隙率一定的氧化铝键合于紧密球核上，粒径30-50u。L6Strongcation-exchangepacking:sulfonatedfluorocarbonpolymercoatedonasolidsphericalcore,30to50口mindiameter.L6强阳离子交换填料：磺化氟代烃聚合物涂渍于紧密球

8、核上，粒径30-50u。L7Octylsilanechemicallybondedtototallyporoussilicaparticles,1.5to10口mindiameter.L7辛基硅烷化学键合于完全多孔硅胶担体，粒径10u。L8Anessentiallymonomolecularlayerofaminopropyl-silanechemicallybondedtototallyporoussilicagelsupport,3to10口mindiameter.L8氨丙基硅烷单分子层化学键合于完全多孔硅胶担体，粒径10u。L9Irregularorspherical,totallypo

9、roussilicagelhavingachemicallybonded,stronglyacidicationexchangecoating,3to10口mindiameter.L910u不规则的完全多孔硅胶具有化学键合的强酸性阳离子交换涂层。L10Nitrilegroupschemicallybondedtoporoussilicaparticles,3to10口mindiameter.L10氰基团化学键合于多孔微粒硅，粒径3-10u。L11Phenylgroupschemicallybondedtoporoussilicaparticles,1.5to10口mindiameter.L11

10、苯基化学键合于多孔微粒硅，粒径3-10u。L12Stronganionexchangepackingmadebychemicallybondingaquaternaryaminetoasolidsilicasphericalcore,30to50口mindiameterL12由四元胺化学键合于精密硅球核形成的强阴离子交换填料，粒径30-50u。L13Trimethylsilanechemicallybondedtoporoussilicaparticles,3to10口mindiameter.L13三甲基硅烷化学键合于完全多孔硅胶，粒径3-10u。L14Silicagelhavingachem

11、icallybonded,stronglybasicquaternaryammoniumanionexchangecoating,5to10口mindiameter.L14具有强碱性四元胺阴离子交换涂层的10u硅胶化学键合相。L15Hexylsilanechemicallybondedtototallyporoussilicaparticles,3to10口mindiameter.L15己基硅烷化学键合于完全多孔性微粒硅，粒径310u。L16Dimethylsilanechemicallybondedtototallyporoussilicaparticles,5to10口mindiamete

12、r.L16二甲基硅烷化学键合于完全多孔性微粒硅，粒径310u。L17Strongcationexchangeresinconsistingofsulfonatedcrosslinkedstyrenedivinylbenzenecopolymerinthehydrogenform,7to11口mindiameter.L17由磺化的苯乙烯二乙烯基苯交连共聚物组成的氢型阳离子交换树脂，粒径711u。L18Aminoandcyanogroupschemicallybondedtoporoussilicaparticles,3to10口mindiameter.L18氨基和氰基化学键合于多孔微粒硅，粒径3

13、-10u。L19Strongcation-exchangeresinconsistingofsulfonatedcross-linkedstyrenedivinylbenzenecopolymerinthecalciumform,9口mindiameter.L19由磺化的苯乙烯-二乙烯基苯交连共聚物组成的钙型阳离子交换树脂，粒径711u。L20Dihydroxypropanegroupschemicallybondedtoporoussilicaparticles,5to10口mindiameter.L20二甲氧基丙烷基化学键合于多孔硅胶微粒，粒径510u。L21Arigid,spherica

14、lstyrenedivinylbenzenecopolymer,5to10口mindiameter.L21刚性球形苯乙烯-二乙烯基苯共聚物，粒径5-10u。L22Acationexchangeresinmadeofporouspolystyrenegelwithsulfonicacidgroups,about10口minsize.L22由多孔聚苯乙烯凝胶和磺酸基组成的阳离子交换树脂，粒径约为10u。L23Ananionexchangeresinmadeofporouspolymethacrylateorpolyacrylategelwithquaternaryammoniumgroups,ab

15、out10口minsize.L23由多孔聚甲基丙烯酸酯或聚丙烯酸酯凝胶及四元胺基组成的阴离子交换树脂，粒径约为10u。L24Asemirigidhydrophilicgelconsistingofvinylpolymerswithnumeroushydroxylgroupsonthematrixsurface,32to63口mindiameter.L24由乙烯基聚合物和基质表面的无数羟基组成的半刚性亲水硅胶，粒径32u63u。L25PackinghavingthecapacitytoseparatecompoundswithaMWrangefrom100to5000daltons(asdete

16、rminedbypolyethyleneoxide),appliedtoneutral,anionic,andcationicwatersolublepolymers.Apolymethacrylateresinbase,crosslinkedwithpolyhydroxylatedether(surfacecontainedsomeresidualcarboxylfunctionalgroups)wasfoundsuitable.L25能分离MW从100到5000Da化合物的填料（取决于聚环氧乙烷），应用于中性、阴离子和阳离子的水溶性聚合物。聚甲基丙烯酸酯作为树脂基质，与聚羟基化醚（表面含一

17、些残余羧基官能团）进行交连。L26Butylsilanechemicallybondedtototallyporoussilicaparticles,5to10口mindiameter.L27Poroussilicaparticles,30to50口mindiameter.L28Amultifunctionalsupport,whichconsistsofahighpurity,100,sphericalsilicasubstratethathasbeenbondedwithanionic(amine)functionalityinadditiontoaconventionalreversed

18、phaseC8functionality.L29Gammaalumina,reversedphase,lowcarbonpercentagebyweight,alumina-basedpolybutadienesphericalparticles,5口mdiameterwithaporediameterof80.L30Ethylsilanechemicallybondedtoatotallyporoussilicaparticle,3to10口mindiameter.L31Astronganion-exchangeresin-quaternaryaminebondedonlatexpartic

19、lesattachedtoacoreof8.5口mmacroporousparticleshavingaporesizeof2000Aandconsistingofethylvinylbenzenecross-linkedwith55%divinylbenzene.L32Achiralligand-exchangepacking-L-prolinecoppercomplexcovalentlybondedtoirregularlyshapedsilicaparticles,5to10口mindiameter.L33Packinghavingthecapacitytoseparateprotei

20、nsof4,000to400,000daltons.Itisspherical,silica-basedandprocessedtoprovidepHstability.L34Strongcation-exchangeresinconsistingofsulfonatedcross-linkedstyrene-divinylbenzenecopolymerintheleadform,about9口mindiameter.L35Azirconium-stabilizedsphericalsilicapackingwithahydrophilic(diol-type)molecularmonola

21、yerbondedphasehavingaporesizeof150.L363,5-dinitrobenzoylderivativeofL-phenylglycinecovalentlybondedto5口maminopropylsilica.L37Polymethacrylategelpackinghavingthecapacitytoseparateproteinsbymolecularsizeoverarangeof2,000to40,000D.L38Methacrylate-basedsize-exclusionpackingforwater-solublesamples.L39Hyd

22、rophilicpolyhydroxymethacrylategeloftotallyporoussphericalresin.L40Cellulosetris-3,5-dimethylphenylcarbamatecoatedporoussilicaparticles,5口mto20口mindiameter.L41Immobilizeddacidglycoproteinonsphericalsilicaparticles,5口mindiameter.L42Octylsilaneandoctadecylsilanegroupschemicallybondedtoporoussilicapart

23、icles,5口mindiameter.L43Pentafluorophenylgroupschemicallybondedtosilicaparticles,5to10口mindiameter.L44Amultifunctionalsupport,whichconsistsofahighpurity,60,sphericalsilicasubstratethathasbeenbondedwithacationicexchanger,sulfonicacidfunctionalityinadditiontoaconventionalreversedphaseC8functionality.L4

24、5Betacyclodextrinbondedtoporoussilicaparticles,5to10口mindiameter.L46Polystyrene/divinylbenzenesubstrateagglomeratedwithquaternaryaminefunctionalizedlatexbeads,10口mindiameter.L47Highcapacityanionexchangemicroporoussubstrate,fullyfunctionalizedwithatrimethylaminegroup,8口mindiameter.L48Sulfonated,cross

25、linkedpolystyrenewithanouterlayerofsubmicron,porous,anionexchangemicrobeads,15口mindiameter.L49Areversedphasepackingmadebycoatingathinlayerofpolybutadieneontosphericalporouszirconiaparticles,3to10口mindiameter.L50Multifunctionresinwithreversedphaseretentionandstronganionexchangefunctionalities.Theresi

26、nconsistsofethylvinylbenzene,55%crosslinkedwithdivinylbenzenecopolymer,3to15口mindiameter,andasurfaceareaofnotlessthan350m2/g,substrateiscoatedwithquaternaryammoniumfunctionalizedlatexparticlesconsistingofstyrenecross-linkedwithdivinylbenzene.L51Amylosetris-3,5-dimethylphenylcarbamate-coated,porous,s

27、pherical,silicaparticles,5to10口mindiameter.L52Astrongcationexchangeresinmadeofporoussilicawithsulfopropylgroups,5to10口mindiameter.L53Weakcation-exchangeresinconsistingofethylvinylbenzene,55%cross-linkedwithdivinylbenzenecopolymer,3to15口mdiameter.Substrateissurfacegraftedwithcarboxylicacidand/orphosp

28、horicacidfunctionalizedmonomers.Capacitynotlessthan500口mindiameter.L54Asizeexclusionmediummadeofcovalentbondingofdextrantohighlycross-linkedporousagarosebeads,about13口mindiameter.L55Astrongcationexchangeresinmadeofporoussilicacoatedwithpolybutadienemaleicacidcopolymer,about5口mindiameter.L56Isopropylsilanechemicallyb