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4、 sCt r e a tme n t - in du c e dvi ra 1c 1ear a n c e J Nature2 0 0 94 6 1(72 62):39940 1 49E ur op e an As so ci a t i o nf or Study ofLiv er;As oc ia ci o nL a t i noa mericanapar ae 1E stud i ode 1 H ig ado EA S L- -A L E HC1 i ni ca1P r a c t i c eG u i de1in es:N-on i nv asiv et e s t sforeva 1

5、u atio n of 1i verdiseaseseveritandprognosis J .JHepatol,2 015,63( 1 ): 23726 4.50 WA I CT,GREENSONJ K,FONTANARJ,e ta l .A s imp l e n o n i nva s i vei ndexc anp redictboths i g n i f icantf ibrosi sa n d c i rr h o s i si npatients withc h ro n i che p at i tisC J . H ep ato lo gy,2003,38(2):51852

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7、4.52 Mi n i s t ryo fHea l tho f thePe o p l esRepubl i co fCh i na.Upda t e ds tandardsforthed i a g n o s i sa n dt r ea tme n to f pr imaryl ivercancerJ.ChinJHepatol,2 012,2 0( 6 ): 4 19 4 2 6 .( i n ) C h i n e s e中华人民共和国卫生部.原发性肝癌诊疗规范(20 11 年版)摘要J .中华肝脏病杂志,201 2 ,2 0(6):4 1942 6 . 5 3MA R T INI

8、A ,FA T T O VIC H G , GU I D OM,e t a l . H CV gen ot y p e 3an d s q ua mo u sce l l c a r cino maan t i g en( S CCA) I g M ar e i n d e pende nt l ya sso ci a te dwi t hh i s t o l ogi ca lf e a t ure s o f NA S H i nHC V i n f ectedpatients J. JV i ralHepat, 2015,2S , MA I D AM,C A MM ? C ,etal.S

9、teatosisa2014,61(3):523529. t i t i sC 55POYNARDT,MO U S SALL I J ,MUNTEANUM,et al .Slo w r e g r ees si o no f l iv er f ibro si spres u me dbyr epe at e dbi om a rker s J.aft e r vir ol o gi c a lc ureinpa ti ents w i t hc hro niche p a ti tisC JHe pa tol20 13,5 9 (4 ):6 7 5 6 83 .56 MOH A NP ,BAR

10、TO NBA ,N A R K EWIC ZMR,etal.Evalua tingprogressionHepato logy, 2 0 1 3,5 8( 5 )LAME RECH TRW,S T E R L INGRK,NAI S H A D H A MD , e t a l . I r o nl evelsi nhepatocyte sa n dp o r t a l t r a c tc el lspredictpro g re s s i onandou t comeso fp at i e n t swi t ha d v an c edchro n i ch e p at i t

11、i sC J .Gastr o en terology,2011,140(5):1490500.58 DAMEROSIOR,AGHE MO A ,F RAQUEL2(10)800808.54MA C A L U S OFff ectsthe perfti ffnessmeasurisassess mentinormance o f liverse m entfor fibrosp atientswit hg e n och e p aofliverdiseasefromr e p e a tesinchildrenwithchroniche p a t i t i sCetrospect i

12、v es tudy0 1 5 8 6.57t y p elch r o n iJ . JH e p a t o l ,L I M,e tal.Thediagnost i caccu rac yofFibroscanforc irrhos isi si n fluence dby liv er mor p h ometr yinH C Vpatien ts withas u sta i ne dvir o l o g i J . JHep ato l ,2 013,59 (2):2 5 1 25 6ca lre spo ns e 5 9 A KHT ARE , MA N N EVS A AB S

13、 .C ir rhosisr egress ion inhe pat itis Cpa.ti e : n tswith s ustai n ed virolo gi ca lr es pons eafter an t iv ir alth er a py: am eta 一 ana lysi s J. LiverInt201535(1):30 一 3 6 .60 DA MBR O S IORAG H E : MOA ,Ru MIMG,et a a1 .Amor phom etric and immun o h ist oche micalst ud ytoa ss es sthe b en e

14、fitofa su stained vi rolo gica l res po nse inh epatitis C vir u spaJH epato log y201256( 2 ):532 t ient swi thc i r r h o s i s543.61 BEDOS SAP,POYNARDT.Ana l g o r i th mf orthegradingo fact i v i t yi nc h r o n i ch e p a t i t i sC.TheMETAVIRCo ope rativeStudyGroup J .Hepatolog y ,1996,2 4 ( 2)

15、 :289293.62 K I MSu , OHHJ,WAN L E S SIRetal.Th e Lae nne cst agi ng s y s t em forhistologica l s ub cl as s i f i cation ofcirrh osi si su sefu l f o r stratification ofp rognos i si npa t i en t swi t hl i v e r cirrh0sisJ JHePat0 1 ,20 12 ,57( 3 )5 56一 5 63 631H UA NGYd eB O ERWEA D A MSL A ,e t

16、 aa1 .I mag ean a1 ysi s0 f1 iV erbi 0P s ysamP1 esmeas u re sf ibr0 sis an dpr e d icts c1i ni ca1 J JHePa t01 , 201461 (1)2 2一27 0 utc0 m e 6 4 D INGH ,MAJJWAN GWPE TAL A s se s s ment0 f1 iV erf ib r0sisT he r e1 a t i0nsh iPbe tw e en p 0 intshearw aVee 1 ast0 graJ 1 JG a str0 enter0 1P h yandqu

17、 an tit at iV ehist01 0gi c a1 ana.1ysis ,2015 , 3 0( 3 )5 53 一 5 58 H eP at016 51J oH:N-B AP T IST E A AT O MLIN S ONG ,H S UP C ,e ta 1S ust a in e dres P0 n d ershaVe b etterqua1 i ty 0 f1if eandP r0d u ctiVityc0m par e dw i t htr eatme ntfa i1 u res 1 0 ng aft er antiVira 1 the raPy f 0r J A m J

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19、NF T rea tmeent0fheP a ti tisBa n dCin chi1dr e n J 1 M inerVaPe d i atr ,20 1 4,66(5):473489.68 MORGANRL,BAACKB,SMI THBD,e ta l.Erad ic at io nofhepat i t i sCviru si nfectio nandthed eve1 o p me nto fhepat o ce1: ame t aa na1 y s iso fobse r v at i o na 1 studies 1 u 1 a r c a r c i n o ma J. A nn

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51、 e a t me n t o f H C Vwi t hA BT 4 5 0/romb i tasvi randd as abuv i r wi t hr i b a v i r i n J . NE ng 1 JMe d , 2 0 14, 370(17) : 15941603. 112 F E RENCIP,BERNSTEI ND ,LALEZARIJ,e ta 1 . AB T 4 5 0/ r omb i t a s v i randdasabuv i rwi t ho rwi t h o u tr i b a vi r inf or H C V J . NE n g 1 J Me

52、d ,2 0 1 4,3 7 0(21):19831992.113 ZEUZEMS,JACOBSONI M,B AYKALT,e ta 1 .R et r eatme n t o f H C Vwi t hA B T 4 5 0 / r omb itasv i randdas abuv i rwi thr i bav i r i nJ .NE ng 1 JMe d , 2 0 1 4, 3 7 0 ( 1 7 ) : 1 6 0 4 1 6 1 4 . 1 1 4 ANDREONEP,COLOMBO MG ,ENEJOSAJV,e ta1.ABT 450,r i t oGastroente r

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