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1、414 cases of postmenopausal bleedingAnalysis of Clinical PathologyAbstractObjective Toinvestigatethecauseofpostmenopausalbleeding.Methodssub-curettage,hysteroscopy,biopsyandothermethodsofXishuangbanna 414 cases of postmenopausal bleeding inpatientswithclinicalandpathologicalanalysis,tounderstand the
2、 reasons for bleeding The results cause ofpostmenopausal bleeding non-organic factors accountedfor 91.30%,accountingfor8.70%ofmalignantlesionsConclusionpostmenopausalbleedinginbenignlesionsmainlywithprolongedpost-menopausalpatientstheprevalenceofendometrialcancerincreased,reachedapeak 10 to 15 years
3、, 15 years aftertheprevalencedecreased.Keywords Clinical analysis of abnormal uterinebleedingaftermenopauseandpathologicalanalysisBleedingaftermenopauseisthecessationofmenstruation vaginal bleeding after a year, mainly referring to the internal genitalia of non-organic, benign1and malignant lesions
4、caused symptoms due to complexcauses, natureis difficultandthereforemay appearonolder womenaftermenopausetheuterusbleeding,stillregardedas adangersignal.Withthedevelopmentofmedicalscienceandthepopularizationofmedicalknowledge,postmenopausalbleedingcausedbymalignantlesionsdecreasedthe proportionof,pr
5、imarilydue to non-organic disease, followed by benign lesions. Inthis paper, Over the past 10 yearsinourhospitalgynecologyclinicof414 patientswithpostmenopausalvaginal bleeding of clinical data for analysis.1Clinicaldata1.1GeneralInformationJanuary 2001 - January 2010 at the gynecological hospital a
6、dmitted 414 cases of postmenopausal bleeding, aged 41 to 82 years, mean 61.5 years, natural menopause 1 to 41years, all cases underwent diagnostic curettage and (or hysterectomy and pathological examination.1.2 Results1.2.1 postmenopausal bleeding inpatientswithpathologicalanalysisofallpatientswithe
7、ndometrialbiopsyandendometrial(orhysterectomy2specimenswereconfirmedby pathologicalexamination.Pathologic diagnosis of atrophic endometrium 167 casesaccounting for 40.34%, endometrial hyperplasia 153 casesaccountingfor36.96%,39casesofsecretoryphaseendometriumaccountedfor9.42%,36casesofendometrialcan
8、cer,accountingfor8.70%,endometritis,19 cases accountingfor4.59%,of which5 cases of IUDdue.1.2.2 The causes of bleeding and the relationship between menopause in Table 1. Table 1 menopause and causes of bleeding (eg1.2.3Endometrialcancerandmenopauseandmenopause, menopausal age, relationship with the
9、time,bleedinginpatientswithendometrialcancer,theratioincreased,reacheda peak10 to 15 years,15 yearsafterendometrial cancer patients disease rate decreased gradually. Links to free discussion paper download 2Womenentermenopause,menstrualcrampsnolonger,if morethan1 year andpostmenopausalvaginalbleedin
10、g,oftenhaveearlysignsofdisease.3Postmenopausal vaginal bleeding, the most common site is the vulva, vagina and uterus which is the most common bleeding, but also the most complex. postmenopausal vaginal bleeding are benign but also malignant.Most malignant tumors caused by bleeding complicated by a
11、series of malignant disease symptoms,poor physical fitness, weight loss, fatigue, fever, bloody vaginal discharge foul-smelling, etc., but no significant effect of antibiotic treatment.Thedisease isthe key to early detectionandearly treatment.Vaginalbleeding,itisnecessarytoobservegoodpersonalhygiene
12、to prevent infections,particularly vaginal and even more so when you have beenscented.Postmenopausalbleedingisasymptomof avarietyof causes,previouslythoughttobesignoftheattention devoted to cancer in this group show 378 casesof dysfunctionaluterinebleedingaccountsfor91.3%,suggesting that in patients
13、 with postmenopausal bleeding,non-organicdiseases,inwhichcaseestrogeninpostmenopausalwomenhormoneata lowlevel,while4FSH is high, high FSH to stimulate the contraction of theovary,theovariancorticalstromalcell proliferation,secretionof estrogendirectly ontheendometrium,althoughcorticalatrophyin postm
14、enopausalovariestoproduce estrogen decrease, However, ovarian stroma andthe adrenalcortexcanstillproducemalehormones,androgenscanbe transformedintoestrone,thephenomenonofendometrialhyperplasiacanbepresented in addition, the early years of menopause, somewomen,ovarianfunctionhasnotbeen fullydepleted,
15、asmall amount of estrogen in savings under the action ofhormones,endometrialhyperplasia,whenestrogenfluctuations that may cause uterine bleeding 1. atrophicendometrium in postmenopausal bleeding may also occur,the datashow thatnon-organic diseasein , proliferativephaseendometrium,and atrophicendomet
16、riumisthemain reason for occurrence of postmenopausal bleeding,whichmayresultfromatherosclerosisoftheuterineendometrialbleeding,endometrialstromaldiffusebleeding,uterineprolapseoruterineobstructionbackward blood circulation, sinus congestion, rupture andbleeding,cysticendometrialglandsrupturecausedb
17、y5bleedinginthissetofdatain 36 casesofendometrialcancer, accounting for 8.70%, although a small number ofcases, but also a long time in line with menopause, age atmenopause the characteristics of a high proportion of lateonset.Causeofvaginalbleedingaftermenopausecomplex and diverse, if timely and th
18、orough examination,clearlythecausesofbleeding,timetogivethebesttreatment, can reduce mortality and improve quality of lifeof older women. Hysteroscopy is considered the positivediagnosis of intrauterine lesions one of the highest ratesof means,itseasyoperation,safety,observe theclear,comprehensive,and
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