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1、生物信息学选择题(Bioinformatics multiple-choice question)The meaning of UTR is (B).A. coding regionB. noncoding regionC. low complexity regionD. open reading frameThe meaning of motif is (D).A. motifB. cross clonal populationC. base pairD. domainThe meaning of algorithm is (B).A. logon numberB. algorithmC.

2、alignmentD. analogyRGP is (D).A. online human Mendel genetic dataB. national nucleic acid databaseC. human genome projectD. rice genome projectThe following Fasta format is correct (B).A. seq1: agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactcccttaB. seq1 agcggatccagacgctgcgtttgctggctttgatgaaa

3、actctaactaaacactcccttaC. seq1:agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactcccttaD. seq1agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactcccttaIf we are trying to do subcellular localization of proteins, we should use (D).A. NDB databaseB. PDB databaseC. GenBank databaseD. SWISS-PROT d

4、atabaseThe meaning of Bioinformatics is (A).A. BioinformaticsB. genomicsC. proteomicsD. epigeneticsIn GenBank, the PLN of the category code means (D).A. mammalian sequenceB. bacterial sequencesC. phage sequencesD. sequences of plants, fungi, and algaeThe meaning of ortholog is (A).A. orthologousB. p

5、aralogC. direct evolutionD. indirect evolutionThe short sequence obtained from the cDNA library is (D).A. STSB. UTRC. CDSD. ESTThe meaning of contig is (B).A. motifB. cross clonal populationC. base pairD. domainThe TAIR (AtDB) database is (C).A. nematode genomeB. Drosophila genomeC. Arabidopsis data

6、baseD. Escherichia coli genomeThe meaning of ORF is (D).A. regulatory regionB. noncoding regionC. low complexity regionD. open reading frameMRNA 5 end has (A) structure.A. hatB. tailC. hats and tailsD. polynucleotideUsing the CNKI database (CNKI) to find the subject of the analysis, the expansion pr

7、otein family protein sequence was published in the third issue of journal bioinformatics seventh in 2008 (C).A., page 3-5B., page 93-95C., page 193-195D., page 293-295At present, the main method for statistical analysis of microarray data is (C).A. chi square testB. correlation analysisC. cluster an

8、alysisTest of normal distribution of D.The meaning of SAGE is (A).Continuous analysis of A. gene expressionB. polyacrylamide gel electrophoresisC. genome analysisD. two-dimensional electrophoresis analysisThe meaning of domain is (D).A. motifB. cross clonal populationC. base pairD. domainMRNA 3 end

9、has (B) structure.A. hatB. tailC. hats and tailsD. poly cytosineThe human non redundant gene database in NCBI is (A).A. UniGeneB. UniProC. UniRefD. URFThe meaning of alignment is (C).A. logon numberB. algorithmC. alignmentD. analogyEntrez uses several logical operators to make the most basic restric

10、tions on keyword retrieval (C)1 kinds of A.2 kinds of B.3 kinds of C.4 kinds of D.Microsatellite markers are (C).A. RFLPB. SNPC. SSRD. RAPDThe submission sequence to GenBank, the program used can be (D).A. EntrezB. SRSC. MedlineD. BankItPDB is a protein (B).A. classification databaseB. structure dat

11、abaseC. phantom databaseD. domain databaseRestriction fragment length polymorphism markers (A).A. RFLPB. SNPC. SSRD. RAPDThe meaning of CDS is (A).A. coding regionB. noncoding regionC. low complexity regionD. non regulatory regionThe construction of the evolutionary tree tool is (C).A. BLASTB. Clust

12、alWC. MegaD. GCGThe meaning of analogy is (D).A. logon numberB. algorithmC. alignmentD. analogyIn eukaryotes, the sequence of the 5 start codon AUG of a gene cDNA conforms to (A) rules.A. KozakB. AU. AGC. SDD. Poly (A) nAfter the nucleic acid sequence is translated into a protein sequence in 6 stran

13、ds, the sequence of proteins is searched. The database uses the program (B).A.blastpb. blastxc. tblastnd. tblastx利用pubmed文献数据查找论文 transgenic plants of petunia hybrida harboring the cyp2e1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde 的第一作者是 (d).a. xian

14、g tb. bao lli p c.zhang q d.基本局部比对搜素工具是 (c).a. megab. clustalwc. blastd. gcg被誉为 生物信息学之父 的科学家是 (d).a. dulbeccos modified eagleb. sangerc. 吴瑞d. 林华安ddbj的含义是 (c).a. 美国国家生物信息中心b. 欧洲分子生物学实验室c. 日本dna数据库d. 中国基因组研究中心利用pubmed文献数据查找发表在 nature, 2012, 487 (7405): 43 - 45 上的论文题目是 (d).a. a map of the cis regulator

15、y sequences in the mouse genomeb. the human cst complex is a terminator of telomerase activityc. tumours: less lactation may explain cancer rised. stem cells: a sporadic super state利用pubmed文献数据查找论文 cancer epigenetics: from mechanism to therapy 作者的单位是 (c).a. university of californiab. university of c

16、olumbiac. university of cambridged. university of chicago单核苷酸标记是 (a).a. rflpb. snpc. ssrd. rapdgenbank数据库的基本信息单位是 (b).a. fastab. gbffc. gcgd. asn. 1omim是 (a).a. 在线人类孟德尔遗传数据库b. 国家核酸数据库c. 人类基因组计划d. 水稻基因组计划多序列比对工具是 (b).a. blastb. clustalwc. megad. gcgembl的含义是 (b).a. 美国国家生物信息中心b. 欧洲分子生物学实验室c. 日本dna数据库d.

17、 中国国家基因组研究中心accession number的含义是 (a).a. 登录号b. 算法c. 比对d. 类推est的含义是 (a).a. 表达序列标签b. 序列标签位点c. 高通量基因组序列d. 人工合成序列利用中国知网文献数据库 (中国知网) 查找论文题目是 黄瓜对不同温度逆境的抗性研究 作者的单位是 (a).a. 天津市黄瓜研究所b. 中国农业科学院c. 中国科学院d. 中国农业大学没有直接参与完成人类基因组计划的国家是 (c).a. 英国b. 中国c. 俄罗斯d. 德国blast结果中hsp的含义是 (d).a. 空位b. 期望值c. 过滤d. 高分配对片段genbank登录号为

18、scu49845的序列, 其dna产度是 (d).a. 1028 bpb. 9 bpc. 4028 bpd. 5027 bpgenbank数据库中的登录号aar19268是 (a).a. 水稻的dna序列b. 水稻的蛋白质序列c. 人类的dna序列d. 人类的蛋白质序列在真核生物的一个基因内含子两端, 即外显子 / 内含子拼接边界处, 其符合 (b) 规则.a. kozakb. the.agc sdd. poly (a) n蛋白质信号肽的预测工具有 (d).a. nnpredictb. predictproteinc. singaldd. singalpbase pair的含义是 (c).a.

19、 基序b. 跨叠克隆群c. 碱基对d. 结构域proteomics的含义是 (c).a. 生物信息学b. 基因组学c. 蛋白质组学d. 表观遗传学根据大量est具有相互重叠的性质, 通过计算机算法获得cdna全长序列, 这种克隆基因的方法是 (b).a. 重叠克隆b. 电子克隆c. 基因步移d. 基因重组隐马尔科夫模型的代号是 (a).a. hmmb. cddc. htgsd. gssentrez数据库中的剪贴板的容量是 (a).a. 500条记录b. 1000条记录c. 5000条记录d.10000 recordsThe meaning of UTR is (B).A. coding reg

20、ionB. noncoding regionC. low complexity regionD. open reading frameGenBank is (B).A. online human Mendel genetic dataB. international nucleic acid databaseC. human genome projectD. rice genome projectUsing the CNKI database (CNKI), the title of this paper is the ultrastructure and photosynthetic cha

21、racteristics of leaf chloroplasts of cucumber hairless mutants, the first author is (A).A. Cao ChenxingB. Zhang SongC. Guo HongyunD. Guo YankuiAccording to the study, the real coding region of proteins in the human genome is only DNA (B).A. 1-2%B. 3-5%C. 5-10%D. 10-20%The meaning of LCR is (C).A. co

22、ding regionB. noncoding regionC. low complexity regionD. open reading frameIf we are trying to do subcellular localization of proteins, we should use (D).A. NDB databaseB. PDB databaseC. GenBank databaseD. SWISS-PROT databaseUsing PubMed literature data to find papers, A, whole-cell, computational,

23、model, predicts, phenotype, from, genotype was published in the Cell Journal (C).A., Vol. first, issue fiftieth, page 389-391B., Vol. first, issue fiftieth, page 389-401C., Vol. second, issue 150th, page 389-401D., Vol. second, issue 125th, page 389-391The meaning of ST in protein motif (motif) is (

24、C).A. amino acid is STB. amino acids are S and TC. amino acids are S or TD. remove any amino acids except S and TBuild phylogenetic trees that should be used (C).A. BLASTB. FASTAC. UPGMAD. FTPPIR is (D).A. nucleic acid databaseB. mRNA databaseC. boot databaseD. protein databaseWhat are the main ways

25、 in which the output graph is used in microarray analysis? (A)A. color cube array representationThe B. is represented in a honeycomb shapeThe C. is represented in black and white dotsD. is represented in color linesWhich of the following is not part of the promoter study? (A)A. CpG Island forecastB.

26、 transcription start point predictionC. glycosylation modificationD. methylation detectionWhat kind of tools does bioinformatics mainly use to realize the storage, retrieval and analysis of biological information in life science research? (A)A. computerB. iPhoneC. satelliteD. mobile phoneThe meaning of HTGS is (C).A. expressed sequence tagsB. sequence tagged siteC. high throughput genome sequencesD. sy

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