[生物医药论文精品] 逍遥丸的药理作用与临床应用探讨 毕业论文

技术学院毕业论文论文题目逍遥丸的药理作用与临床应用探讨作者姓名班级学号）系部药学系专业中药学指导教师2009年12月10日2目录摘要（1）关键词（1）前言（1）1资料与方法11一般资料（1）12方法（2）2结果（2）3分析与讨论31治疗乳腺增生症（3）32对月经不调的影响（4）33对失眠抑郁的治疗（5）结论（6）致谢（7）参考文献（7）1逍遥丸的药理作用与临床应用探讨摘要目的探讨逍遥丸治疗肝郁血虚各类疾病A1A0A2的临床疗效。方法选取河南省中医一附院妇科肝郁血虚患者60例，采用逍遥丸加减，联合使用的方法，治疗女性乳腺增生，月经失调，失眠抑郁。结果对成人乳腺增生，月经不调，失眠抑郁组总有效率947。结论逍遥丸对乳腺增生，月经不调，失眠抑郁患者有良好的治疗或辅助治疗作用。关键词逍遥丸，乳腺增生，月经不调，失眠抑郁，临床疗效，探讨前言逍遥丸来源于宋代太平惠民合剂局方，为医圣张仲景的名方四逆散加减而成，高血压、糖尿病、肾炎在历代中医临床中广泛应用，清代著名医学家叶天士称G17202G1866为G256女科圣G14659G257。G257。G4439G14033G9052G19512G3252肝G8680郁结G5114来的G16844G3822G11163G10378，G11107G17902G8680G7438，调G14422人G1319G1881G8680血G8503G5132G17828G15904，用G2530使人G8680血G8981G11033、G2620G17535G14310G17878，G6937G5483名G256逍遥丸G257。G1866G11013G7624G14005G5415G5414G11345G14433G11345G7427G708G9830G709G14595G14503G10988G14621G15192G14667生G4016G12573组成，G7624G14005G708G2631G17775，G2469散，G2543G14659，性G1571G1949，G4581G19463肝G13978经G5353经G14659G709G11107肝G16311郁G1872清郁G9921G727G5415G5414、G11345G14433G1871血G8975血G7592肝，G14595G14503、G11345G7427、G10988G14621G1593G14098G9195G9299G11422G8680，G15192G14667G708G1949G709散郁G19512G9921，生G4016G708G9921G709G19489逆G2656中，G1861G3875G11107肝G16311郁、G1871血调经、G1593G14098G2656中G1055效A3A5A4。G1866中G7624G14005G708G2469散G709、生G4016G708G9921G709、G15192G14667G708G1949G709，G4518G9921G11468G8994。G1866为G14310肝G16311郁的代G15932方剂，G2460G14033G1871血调经，G15999历代中医临床G2928用。G4439G19036对肝G8680郁结，G14033有效G6925G2904G3252肝G8680郁结G5353G17227的G5785G13502失调G2462G14028G13973G13972G11183、月经不调、乳G6163G13971G3371G2462G13972G11183G12573G11163G10378，G11107G17902G8680G7438，调G14422人G1319G1881G8680血G8503G5132G17828G15904。G7424G11752G12362选取河南省中医一附院妇科G2100G27G51926月G14279G21009G51929月的60例肝郁血虚患者，应用逍遥丸加减治疗，G1820G6265G2590G3926G991。1资料与方法11一般资料选取G14659剂科G2100G27G51926月G14279G21009G51929月的60例肝郁血虚患者，G5192G21848G3355G951G20G272G4693，G7380G4579G209G4693，G7380G3835G240G4693，平G3355G22G24G4693。患者中乳腺增生G210例，月经失调G210例，失眠抑郁G210例。G6164有患者G16798G7041G3355参考人民卫生出版社第六版G1881科学。乳腺增生组G19512了疼G11183、G13971G3371外，患者在G5785G13502上必有烦躁，易怒，恐惧G12573，生理上有功G14033G991G19489G727月经不调组的G11163G10378G14098G8680急躁，G5785G13502变化，G1881分泌失调，肌肤失去色泽，出现斑点G727失眠抑郁组G15932现为入睡困难、浅睡易醒、醒G2530难以入睡、G3822梦、G11345天萎糜不振、四肢无力、反应迟钝、工作效率低G991、头G11183、没有食欲、G14028部难受、记忆力减退G12573。12方法G6164有患者采用逍遥散原方或根据具G1319方证加减使用的方法，7G20G24天为一个疗程。逍遥散的配方半夏G708汤浸，洗7遍，焙G709G21两，枳实G708去瓤，麸G9830G709G20两，槟榔G708锉G709G20两，赤G14595G14503G708去粗皮G709G20两。一个疗程G2530观察G1866结果。2结果G15932G20实验前患者基G7424G11163G10378G5785况G15932实验患者人数G11163G10378乳腺增生G210疼G11183、G13971G3371，在G5785G13502上必有烦躁，易怒，恐惧月经不调G210G14098G8680急躁，G5785G13502变化，G1881分泌失调，肌肤失去色泽，出现斑点失眠抑郁G210入睡困难、浅睡易醒、醒G2530难以入睡、G3822梦、G11345天萎糜不振、四肢无力、反应迟钝、工作效率低G991、头G11183、没有食欲、G14028部难受、记忆力减退G15932G21实验G2530患者G5785况G15932有效患者人数G11163G10378乳腺增生G210基G7424G9052失月经不调G210有G6164好转失眠抑郁G210基G7424G9052失，睡眠质量有G6164好转G15932G22实验前G2530数据分析3实验患者有效患者有效率总有效率乳腺增生G210G2099G249G22G224月经不调G210G20G2790失眠抑郁G210G2099G24乳腺增生患者组G210例乳G6163G13972G11183G9052失，乳腺硬韧，增厚区域G9052失或显著缩G4579、质软，只有一例G11163G10378只是有G6164缓G16311治疗乳G6163G13971G11183、心烦不眠。有利于G6925G2904G727月经不调组治疗乳G6163G13971G11183、经闭经G11183，心烦不眠，有利于G6925G2904患者的低落G5785G13502，G1866与G16844G14659合剂，对治疗月经不调有显著效果，G19512两人G6925G2904不明显G727失眠抑郁组缓G1319G1881郁结的肝G8680，G14033G14310肝G1593G14098、G1871血调经，G1866是治疗抑郁G11163不可G3822G5483的良G14659。总有效率为9G22G224。3分析与讨论31治疗乳腺增生症乳腺增用G22生是近G5192来G2469病率较高的妇女病G1055一，此病好G2469于生育G7438G14033旺盛的育G21848G7411妇女，G1866临床G15932现为G2620G7411性或G19762G2620G7411性的乳G6163疼G11183，疼G11183局G19492在乳G6163的G7588个区域或G9053G2462G2052G6984个乳G6163，G11163G10378一G14336在月经G1055前明显。G16314G16798乳腺组G13467局部增厚或G20075G12902G7691、G7477G13046G10378G6925变，G16314G11183G5461G19463性。现代医学G16760为G1866G2469病原G3252与G2377G5046分泌G19616G4393G9620G13044功G14033失调有G1863，G17819G3822的G19616G9620G13044G19283G7411G2062G9620乳腺组G13467，使G1055G17819G5242增生G2656G3809G7099不G1852。中医学G16760为乳腺增生为肝郁G8680G9394、G1926G1231失调、G11204G9144G1969结而G5430成。G7094G5460有部分病人采用G57G40、G57G376、G11884化G19090治疗，G1306疗效不G12295G4462，G2490外有部分病人采用G989G14531G8699G14030G2462G1866G15905生G10301治疗，G15441G9994疗效G13955G4462，G1306此类G14659G4396在G1584G14659反G5389G2462G9520在性肝G14051G6451G4487G12573G2115作用4。G6164以中G14659治疗乳腺增生成了医生G2656患者的G20330选，中成G14659乳G11306G9052G10267中G9035G15311、G7130G5079、G7420G20333、G17842G13740G11107肝理G8680、化G11204、软G3374散结，G21587G16294、G989G983、G13430G14469、G21493血G15288G8975血G9052G13971、散结G8502G11183，G10584参G1949血G9375G19464，G14982G1856G14533、G17842G13740G12573清G9921G16311G8614，G1872G8856肝G9791，G1852方G11468G1126配G1249G1861G17227软G3374散结、G8975血G9052G11164、清G9921G16311G8614G1055功G14033。逍遥丸G14595G14503G10988G9141、G12079G11204G15904G8712，G7624G14005、G15192G14667清G9921G16311G8614、G11107肝G16311郁，G5415G5414，G11345G14433G15929血，G11345G7427、G10988G14621G15929G8680，G1852方G17902G19463G15904G8712，G15929G8680G15929血，G11107肝G16311郁。两G14659结合使用G2339调性G5390，G3355具有G6338G6251G19616G9620G13044，调G14422G1881分泌G1055作用。在治疗G210例患者中，显效为G209人，缓G16311为G20人，总有效率为9G24。在G6984个治疗G17819程中G7422G2469现不良反应。乳G11306G9052G10267联合逍遥丸治疗乳腺增生G11163效果显著，G2115作用G4581，G1552G5483G6524广。4G5046功G14033失调G15G19616G9620G13044分泌G17819G3822G15而G1457G6264乳腺的G4393G18242减G4581或乳腺G13466G14002对G9620G13044反应G5334G5132G15G19616G9620G13044反G3809G2062G9620乳腺G4579叶G15G14280G1866G17819G5242增生变硬G2588结G14422G10378。G3252此乳腺疾病G3822G2469生于性G9620G13044分泌旺盛G7411G24。中医G16760为G15乳腺增生G11163G4658于G256乳G11306G257G14551G11080G15G3822为G1926G1231失调G15肝G13975不G2656G15肝G14098两G1272G5353G17227。好G2469于G5785G13502不G1351、G9978G15397、G12946神紧张、工作或社会压力G17819G3835G12573育G21848妇女G15用中医理论可以G16311释为G5785志G1881G1272G15肝郁G11204积于G13975络G15G14280使G13975络不G11033G15G8680血瘀G9394而结为包G3371。临床上使用逍遥丸具有G14310肝理G8680、化G11204散结的功效G15使用G2530部分乳腺增生患者的G11163G10378会有G6164缓G16311。桂枝G14595G14503胶囊出自金匮要略中的桂枝G14595G14503丸6G15G11013桂枝、G14595G14503、牡丹皮G15G14433G14659、桃仁组成G15具有G8975血化瘀、调G2656G8680血、软G3374散结、G6251G19616G9620G13044的作用G15G6937可以收G2052较好的疗效G15并且G21种G14659G10301有效率G11468似、价格低廉、用法简单无G8614G2115作用G15可以G19283G7411使用。从普查中随G7438抽取G2100例经G17819临床检查、LG40G20G210G21乳腺G16798G7041仪扫描、彩色G37超G12573G16798G7041明确的乳腺增生G11163患者G15G5192G21848G7380G4579G210G4693G15G7380G3835G246G4693G15平G3355G224G21G4693单侧7G22例G15双侧G20G217例G15病程G19283短不一。将G2100例患者随G7438分为G21组G15G1866中G2000例使用桂枝G14595G14503胶囊纯中G14659制剂G15主要成分是桂枝、G14595G14503、丹皮、桃仁G12573G15具有G8975血化瘀、G9052G13971散结、调G14422G1881分泌的作用治疗。G2490G2000例使用逍遥丸纯中G14659制剂G15主要成分是G7624G14005、G5415G5414、G11345G14433、G15192G14667G12573G15具有G11107肝理G8680、调G14422免疫G2656G1881分泌平衡的作用治疗。桂枝G14595G14503胶囊G22G12902/次0G22G20G/G12902G15每日G22次G15饭G25300G24G20H温开G8712送服G15G17842用G22个疗程G20个G1881分泌G2620G7411为G20个疗程G15经G7411G1584服G15用G14659G7411间忌G17775辣G2062G9620性饮食G15心G5785G14310G11033。逍遥丸每次G27G12902G15每日G22次G15服用疗程与注意事项同桂枝G14595G14503胶囊。乳腺增生是妇女病的高G2469病种G15在妇女病检出率中占G20330位7G15而且容易恶变。近G5192来G15随着乳腺癌防治科普知识的普G2462G15预防胜于治疗的理念逐渐深入人心G15随着乳腺疾病普查普治工作的深入G15乳腺增生G11163G5483G2052了有效而G2462时的治疗G15患病率逐G5192G991G19489G15这对G19489低乳腺癌的G2469病率具有深远的意义。32对月经不调的影响月经G27为妇女的G8503G5132生理现象，月经的主要成分为血。肝为藏血G1055G14051，主G11107G8856，性G2928G7477达，肝的G11107G8856藏血功G14033对于人G1319G5785志G7477达、G8680血平G2656G17227G2052重要的调G14422作用。月经G17819G4581的病G7438为督、G1231、G1926、G5114脉不调，以G1926G1231不调为主。G5785志不G11033，肝G1055G8680G7438阻G9394，脉络壅塞，血G15904不G11033，G8680G9394血瘀G727或饮食劳倦G1272G14098，化源不足，血G9035亏虚而经G15904量G4581G727或G1820天肾G8680不足，G3822产G6163劳G1926G1231受G6451，G14280G12946血虚G4581，血G90355不盈而月经量G4581。治疗时G1820天不足重在G15929肾，G2530天失调重在治G14098。清代名医叶天士临证指南医案指出G256女子以肝为G1820天，女子G4658G19464，G19464性G1969结易于拂郁，郁而G8680G9394血亦G9394，必妨G14098土。G257据此，以治肝调G14098或肝肾同治为治G7424病G1055要。在治肝调G14098上临床采用逍遥丸G11107肝G16311郁、G1593G14098G1871血调经，以取G5483调肝治G14098G1055效果，充分G1319现了G256见肝G1055病，知肝传G14098，G5415G1820实G14098G257的原则。肝主G11107G8856，肝G8680的升G2469主司着G14051腑G8680G7438升G19489G4471G2469。G3926食G10301的G9052化与G6502G8856、G14841G1871成分的G2572收与分G5079、血G9094的G5502G10627与调G14422、G8712G9094的代G16886与调G14422G12573G3355与肝G8680的G11107G8856有G1863。中医学从G19283G7411的医疗实G17353中G16760为，人的G5785志G8975G2172与肝G8680的G11107G8856有G11464G6521的G1863G13007。G14521G5785志不好，肝失G11107G8856，则G14051腑G8680G7438不G4471，无G5430G1055G8680不化，G1866病理变化必G9994G4560G14280G11204、G9791、G8680、血、食、G9299G1055郁，G6937病变G14719G8991，G16844病G11013此而生。逍遥丸对妇科疾病中G3252肝郁血虚G14098G5381而G4560G14280的病G11163疗效显著。G21656G14685G12573G466G20G467G17902G17819G3250G20050近G200G5192来的G7003G10498，对逍遥散的G14659理G11752G12362G17839G15904G13520G17860，证实逍遥散具有调G14422中G7542G14030类神经G17894质、调G6984G1319G1881G9620G13044G8712平、G1457肝、G6251自G11013基G2656G6925G2904G5506G5502G10627G12573G14659理作用。现代G14659理学G11752G12362G1075G15932明G466G200G467，G7624G14005G11350G14539有明显的G19227G19757、G4445G4462作用，G14033G1431G17839人G1319G17805G13548G13007G13491G2656皮质G13007G13491功G14033，对G13975G13940、中G7542神经G12573有明显的生理调G6523作用G727G14595G14503G3822糖有免疫调G14422、G6251G12946神分G16022的作用G727G11345G14433G1075有一G4462的G19227G19757作用，对不良应G9620有一G4462的G6281G6251G2656预防作用G727G5415G5414G6164G2559G6393G2469G8845成分，G14033G6251虚G5381、G6251G17151血，对于子G4479、G2377G5046G12573有双G2533调G14422作用。G16844G14659合用，G16844G11163平G5699，使患者的心理G2533G1593G5259的方G2533转化，G2469G6393生理与心理G11468G1126的积G7509G2339调作用，从而G6925变原有的病G5589心理生理G17819程。逍遥丸为中成G14659，G6670G5114G2462服用方G1427，经G8994实用，患者易于G6521受，G20059具实用G2656G6524广价G1552。逍遥调经G17160G200G16311郁调经作用。方中用G7624G14005G11107肝G16311郁散G9921G15以G15192G14667助G1866G11107达肝G8680。丹皮、G7636子清肝经郁G9921G15G5415G5414、G11345G14433G1871血G7592肝G15G11345G7427、G14595G14503G12079G9299G1593G14098G15G7424方G5132用于肝郁化G9921G6164G14280月经G1820G7411的治疗。G1866为纯中G14659配方G21669G14179G14659，配方中G1838参G15929中G11422G8680G727G11422G8609G14621、G5415G5414、G5322G14005、G13430G14469、没G14659G12573G15929血G8975血，调经G8502G11183，用于血虚萎G21656、G11517G7209心G5772、月经不调、经闭G11183经G727与G10099G3332、G11345G7427G12573配G1249，对G8680血双虚有G5468好的G15929G11422效果。G20333附、G19484皮、G19750皮理G8680G16311郁，调经G8502G11183。G9801G14038G17902经、G12079瘀，治月经失调，产G2530G14157G11183。生G3332、丹皮、G3332G20604皮、G10988G14621、G21626G1920清G9921G1949血、G1871G19464生G8953。G1056G14659与G5415G5414、G20333附、G7420G20333G12573同用，对G4518G1969G8680G9394G11183经有G5468好的疗效。加G1055G7420G17902、G4460桂、G9858G4016、G14600G20333G12573温中散G4518，G17902脉G8502G11183G12573温经G8502血的6G14659剂，使G14659G10301功效事半功G1505。G21656G14461、G5041G14434、G21656G17842、G18214G14433G12573有去G9299G8975血的功效，G2339同G7420G17902G12573散G4518G14659剂，将G1319G1881G4518G18046G6312出。而G7624G14005、G5041G7985子、G7420G20333、G7472仲用于肝G8680郁结、G13973G13919疼G11183、月经不调G12573。远志、丹参G4445神G11422G7246，G12079G11204，G9052G13971。治疗乳G6163G13971G11183、心烦不眠。有利于G6925G2904患者的低落G5785G13502。G1056G20604G21493对G1319虚血亏、肝肾不足、G14098G13975不G1593的人效果G7368G1351。与G16844G14659合剂，对治疗月经不调有显著效果。33对失眠抑郁的影响为G8616较逍遥丸与G8691G16211G8724治疗肝G8680郁结G3423抑郁G11163的疗效G2462G4445G1852性。选G6333G2100G24G51926月G2100G27G51926月在院G19388G16798G4613G16798患者G20G214例。G13447入G7643G1946G311G12538合中G3281G12946神疾病G19568G11873分类方案与G16798G7041G7643G1946G708G22版G709G759G20G21G2469作G16798G7041G7643G1946。G312G5192G21848G305G20G27G4693。G313G8733G4506G4584G20051抑郁量G15932G708G43G36G48G39G709G759G20G22总分G708前G207项G709G305G20G27分。G314中医G17788证G12538合中医病证G16798G7041疗效G7643G1946G759G20G20G256郁病G257的肝G8680郁结G17788证G7643G1946。G6502G19512严重的躯G1319疾病。G6502G19512G18214、G14659G10301G12573依赖G10301质G6164G14280抑郁G10378G5589。G6502G19512G12946神分G16022G11163G2462产G2530抑郁G11163。按数字随G7438方法将患者分为逍遥丸组G2656G8691G16211G8724组。G1866中逍遥丸组6G21例，男G21G24例，女G227例G727平G3355G5192G21848G708G22G24G246G200G229G709G4693G727G7003化程G5242G7003盲4例，G4579学G2052初中7例，初中G2052高中G226例，高中以上G20G24例G727平G3355病程G708G21G2140G21G209G24G709月。G8691G16211G8724组6G21例，男G217例，女G22G24例G727平G3355G5192G21848G708G226G277G2009G20G709G4693G727G7003化程G5242G7003盲G22例，G4579学G2052初中G20G20例，初中G2052高中G220例，高中以上G20G27例G727平G3355病程G708G214G27G24G21G24G204G709月。G21组在G5192G21848、性别、病程、G7003化程G5242方面经齐同性检验，差G5334无G13491计学意义G708PG335500G24G15G21组患者入组前G3926果使用G1866G4439G6251抑郁G14659G10301，G1584G14659洗脱G20G2620，使用单G14030G8699化酶抑制剂G1584G14659洗脱G22G2620服G14659方法，逍遥丸组口服逍遥丸9G，每天G21次。G8691G16211G8724组口服G8691G16211G8724G210MG，每天G20次，视病G5785变化加量，G7380G3835剂量不超G1781960MG。治疗观察G7411间G21组G3355G7422使用G14531二氮卓类G12573G1866G4439G14659G10301，G3355G7422配合心理治疗。疗程为6G2620。G21组在治疗前、治疗G2530G22G2620、6G2620G17839G15904G43G36G48G39评分，治疗G25306G2620G17839G15904不良反应量G15932G708TG40SSG709G2656临床疗效评G4462量G15932G708CGIG40IG709G759G20G21评G4462。同时在入组前、治疗中G2462治疗6G2620分别G17839G15904血、尿G5132规，心电图，肝、肾功G14033，血压，脉搏G12573检查。在入组前G17839G15904各种使用量G15932的一G14280性培训，KAPPA0G27G24。G21组治疗前G2656治疗G2530G22G2620、6G2620G43G36G48G39G2656G3252子分评分G8616较见G15932项目治疗G2530G22G2620治疗G25306G2620治疗前治疗G2530G22G2620G9978G15397躯G1319化06G270G200G20G709G22G70904G210G204G20G709G20G22G210G20G270G2760G20G24G22G709G1319重0G22G2404G27G22G7090G22G20046G22G7090G2740G2270470G240G22G7097G16760识G19568G1187306G270G214G22G7090460G21G21G22G709G20G20G240G2140660G207G22G709日夜变化0G24G220G240G22G7090G21G24044G22G7090G2740G22706G27047G22G709阻G939406G210G20G22G22G7090400G21G24G21G709G22G709G20G21G220G2100G24G270G20G21G22G709睡眠G19568G118730G24G210G207G22G7090G2170G20G22G22G709G20000G21G220G2440G21G20G22G709绝望感07G240G22G22G22G7090G24G200G22G27G22G709G20G2400G24607G270G22G20G22G709总分G20G24G200G224G24G22G7099G21G24496G22G709G21G279G24G22G216G206G20G20G2204G22G709G15932明逍遥丸G2656G8691G16211G8724都G14033显著G6925G2904抑郁G11163G10378，逍遥丸在G6925G2904G9978G15397躯G1319化G2656阻G9394方面优于G8691G16211G8724。抑郁G11163G4658于祖G3281医学的G256郁证G257G14551G11080。中藏经曰G256有G14033悲泣者，有G14033奔走者，有G14033呻吟者，有自高贤者，有自委屈者，有寐而不寤者有不G14033言而声昧者。G257金匮要略妇人杂病脉证并治记载了G4658于郁证的G14051躁G2462梅核G8680G21种病证。G20050松园医镜云G256G5132作叹G5699，或不食。G257这些G6164描G17860的G11163G10378G3355为抑郁G11163的典G3423G15932现。祖G3281医学G16760为G7424病的G2469生与G983G5785G1881G1272、忧思太G17819、肝G8680郁结G12573G3252G13044有G1863，G2469病可急可缓，病位以肝、心、G14098为主，病初G3822实，渐G14279虚实夹杂，久则以虚为主，虚中夹实，终可G1272G2462G14051腑，G14280G8680血、G19464G19463虚G5381，以肝、心、G14098虚为G5132见G759G204。祖G3281医学在治疗抑郁证方面早有G5468G3822的记载。G3926G13044问六元G8503纪G3835论说G256郁G1055甚者，治G1055奈何G257，G256G7420郁达G1055，G9791郁G2469G1055，土郁夺G1055，金郁G8856G1055，G8712郁折G1055。G257元代丹溪心法六郁已将郁证列为一个专篇，提出了G8680、血、G9791、食、G9299、G11204六郁G1055说，创立了六郁汤、越鞠丸G12573G11468应的治疗方剂。G3926出自太平惠民G2656剂局方的逍遥丸，具有G11107肝G16311郁、G1593G14098G1871血的功效，G5414G14433G1871血，以G15929肝G1319，以G2656肝用G727妙在G7624G14005、G15192G14667，G17902心G14157G13975G13940结G8680，芳G20333G11107散，G7420郁达G1055，以遂G1866生生G1055G8680G727配G1249G11345G7427、G14595G14503G11422G8680G1593G14098，G7094可使G14098G1593而不受肝乘，G2460可使G14098G14033化生G8680血以G1871肝G727而炙G10988G14621G11422G8680缓急，G2460可助G14595G14503、G11345G7427以G1593G14098G8680。G16844G14659合用，使患者肝G8680顺G11033，G14098G8680G1593G17828，G8680血顺G11033。G19484修园谓G256方G15441庸陋，G14033G9375G19463明G1055燥，不为无见，G3926谓G7420郁则G9791郁，G9791郁则土郁，土郁则金郁，金郁则G8712郁。今以一方制G7420郁，而G16844郁皆G16311，辗转牵附，学者何G6164依据，甚G19762G6164以治方学G1055G8503轨G1075。G257G759G20G24近G5192来对中G14659的G14659理G11752G12362结果G1075G15932明，逍遥丸具有调G14422中G7542单G14030类神经G17894质，影响G24G43T、G24G43TG21A受G1319，调G6984G1319G1881G9620G13044G8712平、G1457肝、G6251自G11013基G2656G6925G2904G5506G5502G10627、调G14422功G14033紊乱的作用G759G206。而在石菖G14982、G9151G13662G15315、G5064G6131天、G17155叶G12573中G14659中G3355G2469现有G6251抑郁作用的G8975性G10301质，与目前现代医学G6251抑郁G11163G14659G10301的治疗G7438制类似G759G207。G7424G11752G12362G15932明，G17788证G17828用逍遥丸治疗抑郁G11163，总G1319临床疗效与G8691G16211G8724G11468似，在G6925G2904G9978G15397躯G1319化G3252子G2656阻G9394G3252子方面逍遥丸优于G8691G162118G8724。对于治疗G17819程的不良反应，TG40SS总分G2656G7905G10301神经G13007G13491G2115反应方面逍遥丸G3355低于G8691G16211G8724，CGI疗效指数逍遥丸高于G8691G16211G8724，G15932明逍遥丸治疗G2530，G9978G15397G2656躯G1319化G11163G10378明显G6925G2904，并且口G5190、G1427G12204G12573G7905G10301神经G13007G13491的G2115作用明显减G4581，这可G14033G2656中G14659G6984G1319治疗的G7438理有G1863，G2656目前的临床G6265G17959一G14280G759G20G27。G17788证G17828用中G14659治疗抑郁G11163G14033取G5483较好的临床疗效，而且G2115反应G4581，G1552G5483G17839一G8505深入G11752G12362。结论G17902G17819探讨逍遥丸治疗肝郁血虚的各类疾病的临床疗效，G5483出逍遥丸对乳腺增生、月经不调、失眠抑郁患者有良好的治疗或辅助治疗作用。致谢G7424论G7003是在G4560G5084G7484G4581G21869的G5725心指G4560G2656严格要G8726G991G4448成的。从论G7003的选G20076、G16809验论证、G16786计实G7057G2052论G7003的G6788G1901、修G6925、G1196G7783，无不G1969结着G4560G5084的心血G2656G8747G8712。G1972个月来，G5693G5084在学G1076G2656G16809验上对G6117严格要G8726在为人G3800事上G16858G16858G6957G16838，G13485G1116G6117G14719G3835的G2563G12046G2656G5122助。G5693G5084高G4590的G5084G5515、严G16892的治学G5589G5242、G5548G6117的工作G9921G5785以G2462G4497以G5465人、G16838人不倦的G20130G14551，将在今G2530的人生G17959G17347上时时G9620G2181着G6117、G19841G12586着G6117。G1552此论G7003G4448成G1055G19481，G16892G2533G6117G4574G6976的G4560G5084G15932G12046G7380G16814G6382的G16886意G4在论G7003的G6788G1901、修G6925G17819程中，G7484G4581G21869G13781G5084G13485G1116了G9921G5785指G4560G2656G6915G6357G17836G5483G2052了同G12395好G2463在G16780G3822方面的G6915G6357G2656G5122助在G7460G7021的收G19610G19466G8585学G7669提G1391了G3835力G6915G6357。在此，G2533G6164有G1863心G2656G5122助G17819G6117的G20058G4560、G13781G5084、同学G2656G7391G2463G15932G12046G7380G11507G6382的G16886意。同时感G16886G1871育G6117的G10250G8609G2656G1863心G6117的G1158人，G1194G1216在G6117成G19283G2656G8726学的G17959G17347上G13485G1116了G6117无G4625的G1863G10245G2656G14719G3835的G6915G6357，没有G1194G1216的G1196出，G4613没有G6117今天的收G14731，G1158人的G10245是G6117不G7041前G17839的G2172力G4主要参考文献G20G14685G15金G14521G6947逍遥丸G14659理G11752G123