英文文献汇报技巧ppt课件.ppt

MalnutritioninPatientsWithCancer ComparisonofPerceptionsbyPatients Relatives andPhysicians ResultsoftheNutriCancer2012Study JournalofParenteralandEnteralNutritionIF 3 517Publication Jan2017 1 THEMAINCONTENTS 2 1 第 部分 研究背景及目的 3 Malnutritionincreasestheriskoftreatmenttoxicityandimpairsoutcomesofpatientswithcancer Earlynutritioninterventionsarerecommendedinproperlyidentifiedpatientsforimprovingtreatmenttoleranceandpatientsurvival Underestimationofmalnutritionremainsasignificantissuesinceearlyrecognitionofmalnutritionmayallowforearlyoptimizationofnutritioninterventionstosupportpatientsduringtreatment Patientself screeningformalnutritionhasbeenreportedasfeasibleincancer andrelativesmayalsoprovideexternalinformationonnutrition 4 questions Whetherpatientswithcancerand ortheirrelativesareawareofmalnutritionandcouldimprovetheefficacyofnutri tioninterventionsisunclear However thesubjectiveawarenessofmalnutritionbythepatients theirrelat ives andphysicianshasnotyetbeenassessedorcompared 5 Objective Tocomparethevalidateddefinitionofmalnutritionwiththeperceptionsofnutritionstatusbypatients relatives andphysicians Tofindouttheriskfactorsofmalnutrition 6 2 第 部分 研究方法及对象 7 研究方法及对象 Methods TheNutriCancer2012multicentriccross sectionalsurveywasconductedon1predefinedday Thesurveywasconductedin283departmentsofprivateorpublichospitalsin36citiesinFranceonOctober9 2012 andincluded2197patients Eachincludedpatienthadtocompleteaquestionnaire Theatt endingphysicianonthedayofthevisitwasincluded aswellastheclosestrelative whoalsoreceivedquestionnairestocom plete 8 研究方法及对象 Inclusioncriteria patientsdiagnosedwithcancer aged 18years andwillingtocompleteaquestionnaire Malnutritionwasidentifiedasfollows weightloss 5 within1monthor 10 within6months abodymassindex BMI 18 5kg m2inpatientsaged 70yearsor 21kg m2inpatientsaged 70years albu minemia whenavailable 35g Linpatientsaged 70years 9 3 第 部分 研究结果 10 11 Malnutritionprevalenceandstatisticalanalysis Overall 826patientsweremalnourished 39 95 confidenceinterval CI 37 41 withahigherpre valenceinpatientswithliverandpancreaticcancers 12 Malnutritionwasidentifiedin40 40 and31 ofpatientsininitialevolution relapse orremission respectively and27 ofpatientswithlocaldiseasestage 13 Prevalenceofmalnutritionwas39 Physiciansoverestimatedmalnutrition 44 whereaspatientsandrelativesunderes timatedit 24 and25 respe ctively P 001 14 Accordingtoquest ionnaires 57 ofpatientsand61 ofrelativesreportedalowerfoodintake m ainlybecauseofGIsymptoms 15 Nutritionint erventionswererecalledandwerem orefrequentinmalnouri shedpatients 16 4 第 部分 讨论及总结 17 Thisstudyconfirmedthehighprevalenceofmalnutrition 39 inpatientswithcancer Thepercentageobtainedisslightlyhigherthanthe30 9 foundinapreviousstudybyPressoiretal 7 andlowerthanthe43 5 and52 reportedbyNourissatetal 8 andSeguraetal 9 respectively Oneexplanationcouldbethedifferentproportionsofpa tientswithGIlocations 32 inourstudycomparedwith17 and34 inthestudiesbyPressoiretal 7 andNourissatetal 8respectively whileinthestudybySeguraetal 9theproportionofpatientswithpancreaticandlungcancerswashigher 18 Patientsandrelativesunderestimatedmalnutritionwhilephysiciansoverestimatedit indicatingalowawarenessofpatientsandrelativesregardingmalnutritionincancer Furtherstud