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医学免疫学(谭锦泉)演讲人202X-11-11目录01.GENERALINTRODUCTION07.English-ChineseComparison03.IMMUNECELLS05.CLINICALIMMUNOLOGY02.IMMUNEMOLECULES04.IMMUNERESPONSE06.Appendix08.AttachedCompactDiscsGENERALINTRODUCTIONChapter1ImmunityChapter2ImmuneCellsChapter3LymphoidTissuesandOrgansChapter4PathologicalImmunityandIm-muneDiseasesSection1FundamentsofImmunologyChapter1ImmunityInnateImmunityAdaptiveImmunitySection1FundamentsofImmunologyChapter2ImmuneCellsPhagocytesLymphocytesAntigenPresentingCellsSection1FundamentsofImmunologyChapter3LymphoidTissuesandOrgansPrimaryLymphoidOrgansSecondary（peripheral）LymphoidTissuesandOrgansLymphocyteTrafficandRecirculationSection1FundamentsofImmunologySection2BriefHistoryandProspectofImmunologyChapter1EmpiricalImmunologyChapter2ScientificImmunologyChapter3ModernImmunologySection2BriefHistoryandProspectofImmunologyChapter2ScientificImmunologyDiscoveryofPathogensandApplicationofVaccinesDiscoveryandApplicationofAntibodiesCellularImmunityImmunologicalToleranceSection2BriefHistoryandProspectofImmunologyChapter3ModernImmunologyDiversityofAntigenReceptorsDiscoveryofSignalTransductionPathwayDiscoveryofProgrammedCellDeathHematogenesisandDevelopmentofIm-muneCellsImmunologicalApplicationProspectofImmunologyIMMUNEMOLECULESSection3AntigenChapter1PropertiesofAntigenChapter2CharacteristicsofAntigenChapter3FactorsInfluencingImmunogeni-cityChapter4ClassificationofAntigensChapter5Non-specificStimulatorsChapter2CharacteristicsofAntigenSpecificityForeignnessSection3AntigenSection3AntigenChapter3FactorsInfluencingImmunogeni-cityPhysicochemicalPropertiesofAntigensEffectofHostModeofContactChapter4ClassificationofAntigensTD-AgandTI-AgClassificationBasedonRelationshipwithHostSection3AntigenChapter5Non-specificStimulatorsSuperAntigenAdjuvantMitogenSection3AntigenSection4ImmunoglobulinsChapter1OrganizationofImmunoglobulinsChapter2ImmunoglobulinClassesandSub-classesChapter3BiologicalActivitiesofImmuno-globulinsChapter4BiologicalPropertiesandFunc-tionsofImmunoglobulinClassesChapter5AntibodyTechnologyChapter1OrganizationofImmunoglobulinsMolecularStructureofImmunoglobulinsJChainandSecretoryComponentEnzymaticDigestionProductsofImmu-noglobulinsSection4ImmunoglobulinsSection4ImmunoglobulinsChapter2ImmunoglobulinClassesandSub-classesImmunoglobulinClasses，SubclassesandTypesIsotypes，AllotypesandIdiotypesofIm-munoglobulinsSection4ImmunoglobulinsChapter3BiologicalActivitiesofImmuno-globulinsActivitiesofVariableRegionsActivitiesofConstantRegionsSection4ImmunoglobulinsChapter4BiologicalPropertiesandFunc-tionsofImmunoglobulinClassesIgGIgAIgMIgDIgESection5TheComplementSystemChapter1IntroductionChapter2PathwaysofComplementActiva-tionChapter3RegulationofComplementSystemActivationChapter4BiologicalConsequencesofCom-plementActivationChapter1IntroductionComponentofComplementSystemNomenclatureSection5TheComplementSystemSection5TheComplementSystemChapter2PathwaysofComplementActiva-tionClassicalPathwayTheLectinPathwayAlternativePathwayTerminalSequenceandtheMembraneAttackComplexSection5TheComplementSystemChapter3RegulationofComplementSystemActivationSelf-regulationFluid-PhaseRegulatorSolid-PhaseRegulatorSection5TheComplementSystemChapter4BiologicalConsequencesofCom-plementActivationCellLysisOpsonizationandPhagocytosisViralNeutralizationInflammationRegulationofCellsClearanceofImmuneComplexChapter1IntroductionChapter2ClassificationandBiologicalActivitiesofCytokinesChapter3CytokineReceptorsChapter4ClinicalApplicationSection6CytokinesSection6CytokinesChapter2ClassificationandBiologicalActivitiesofCytokinesInterleukinsTumorNecrosisFactorInterferonHematopoieticColony-StimulatingFactorsTransformingGrowthFactorChemokinesChapter3CytokineReceptorsIL-1ReceptoTNF-αReceptorsIL-2ReceptorChemokineReceptorSection6CytokinesSection7MajorHistocompatibleComplexChapter1StructureandGeneticsofMHCChapter2MHCPolymorphismChapter3Peptide-MHCInteractionChapter4HLAandClinicalMedicineChapter1StructureandGeneticsofMHCClassicalMHCGeneComplexMHCMoleculesOtherMHCGenesSection7MajorHistocompatibleComplexChapter2MHCPolymorphismConceptofPolymorphismLinkageDisequilibriumandHaplotypeGenerationandSignificanceofMHCPoly-morphismSection7MajorHistocompatibleComplexChapter3Peptide-MHCInteractionMolecularBasisCharacteristicsSection7MajorHistocompatibleComplexChapter4HLAandClinicalMedicineHLAandGraftRejectionHLARelated-DiseasesHLAandDiseasesSection7MajorHistocompatibleComplexSection8LeukocyteDifferentiationAnti-gensandAdhesionMoleculesChapter1LeukocyteDifferentiationAnti-gensChapter2CellAdhesionMoleculesChapter3ClinicalApplicationofCDMole-cules，CamandMonoclonalAntibodiesAgainstCDMoleculesandCamSection8LeukocyteDifferentiationAnti-gensandAdhesionMoleculesChapter1LeukocyteDifferentiationAnti-gensConceptofLeukocyteDifferentiationAntigensConceptofClusterofDifferentiationSection8LeukocyteDifferentiationAnti-gensandAdhesionMoleculesChapter2CellAdhesionMoleculesIntergrinFamilySelectinFamilyImmunoglobulinSuperfamilyFunctionsofCellAdhesionMoleculesSection8LeukocyteDifferentiationAnti-gensandAdhesionMoleculesChapter3ClinicalApplicationofCDMole-cules，CamandMonoclonalAntibodiesAgainstCDMoleculesandCamElucidationofPathogenesisDiagnosisandPrognosisinClinicalUsePreventionandTreatmentforDiseasesIMMUNECELLSSection9HematopoieticStemCellsChapter2DifferentiationofHematopoieticStemCellsTheFactorsAffectDifferentiationofHe-matopoieticStemCellsDevelopmentofLineage-CommittedPro-genitorsChapter1OriginandSurfaceMarkersofHematopoieticStemCellsOriginofHematopoieticStemCellsSurfaceMarkersofHematopoieticStemCellsSection10CellsofInnateImmunityChapter1PhaseofInnateImmunityChapter2CellsofInnateImmunityChapter3ReceptorsofInnateCellsChapter2CellsofInnateImmunityEpithelialsPhagocytesNeutrophilsMononuclearPhagocytes:theMonocyte-MacrophageSystemNKCellsγ:δTCellsB1BCellsNKTCellsSection10CellsofInnateImmunityChapter3ReceptorsofInnateCellsPattern-RecognitionReceptorsTollLikeReceptorsSection10CellsofInnateImmunitySection11TLymphocytesChapter1TCellOntogenyChapter2SurfaceProteinsofTLymph-ocytesChapter3TLymphocytesSubsetsandFunctionsChapter1TCellOntogenyStagesofThymocyteDevelopmentPositiveandNegativeSelectionofThym-ocytesSection11TLymphocytesChapter2SurfaceProteinsofTLymph-ocytesTCR-CD3ComplexCD4andCD8CoreceptorsCostimulatoryMoleculesMitogenReceptorsSection11TLymphocytesSection11TLymphocytesChapter3TLymphocytesSubsetsandFunctionsHelperTLymphocytesCytotoxicTLymphocytesMemoryTCellsRegulatoryTCellsSection12BLymphocytesChapter1DevelopmentofBLymphocytesChapter2SurfaceMarkersofBLympho-cytesChapter3SubsetsandFunctionsofBLymphocytesChapter1DevelopmentofBLymphocytesTheBCellsDevelopmentintheBoneMarrowTheBCellsMaturationinGerminalCentersSection12BLymphocytesChapter2SurfaceMarkersofBLympho-cytesBCRComplexSurrogateBCRComplexOtherSurfaceMarkersSection12BLymphocytesSection12BLymphocytesChapter3SubsetsandFunctionsofBLymphocytesB1CellsandTheirFunctionsB2CellsandTheirFunctionsImmuneRegulationSection13OrganizationandDiversityofAntigenReceptorGenesChapter1StructureofAntigenReceptorGenesTheGeneStructureofBCRTheGeneStructureofTCRChapter2RearrangementofAntigenReceptorGenes

Chapter3TheDiversityAntigenRecep-torGenesBCRTCRIMMUNERESPONSESection14InnateImmuneResponseTheSkinandtheMucosalSurfacesImmuneCellsInvolvedinInnateImmuneResponseHumoralProteinsofInnateImmunityChapter1ComponentsInvolvedinInnateImmuneResponsePathogenAssociatedMolecularPattersn（PAMPs）PatternRecognitionReceptor（PRR）Chapter2TheRecognitionMechanismofInnateImmuneResponse

Chapter3TheBiologicalSignificanceofInnateImmuneResponseChapter1AntigenPresentingCellsMPSAntigenProcessingandPresentationbyDendriticCellsAntigenProcessingandPresentationbyBLymphocytesChapter2AntigenProcessingandPrese-ntationProcessingofExogenousandEndogenousAntigensMHCandAntigenProcessingandPre-sentationCD1RelatedAntigenPresentationSection15AntigenPresentationSection16TCellsRecognitionsandRes-ponsesofAntigensChapter1TCellsRecognitionofAntigensChapter2SignalsforTCellsActivationChapter3SignalTransductionofTCellActivationChapter4TranscriptionFactorActivationandGeneExpressionChapter5FunctionsofEffectorTCellsSection16TCellsRecognitionsandRes-ponsesofAntigensChapter2SignalsforTCellsActivationStimulatorsofTCellsActivationDoubleSignalsforTCellsActivationSection16TCellsRecognitionsandRes-ponsesofAntigensChapter3SignalTransductionofTCellActivationReceptorCross-IinkingCytoplamicSignalingbyTCRSection16TCellsRecognitionsandRes-ponsesofAntigensChapter5FunctionsofEffectorTCellsFunctionsofCD4+TH1CellsFunctionsofCD8+CytotoxicTCellsSection17BCellRecognitionandResp-onseofAntigensChapter1BCellResponsetoTCell-DependentAntigenChapter2BCellResponsetoTCell-Independent-AntigenChapter3RulesofAntibodyProductionChapter4MucosalImmuneResponseSection17BCellRecognitionandResp-onseofAntigensChapter1BCellResponsetoTCell-DependentAntigenClonalSelectionandAntigenRecogni-tionofBCellsSignalingbyBCRComplexandBCellCoreceptorsEffectsofTHCellsandInteractionBetweenTHandBCellsDevelopmentandDifferentiationofBCellsinGerminalCentersSection17BCellRecognitionandResp-onseofAntigensChapter2BCellResponsetoTCell-Independent-AntigenBCellResponsetoType1ofTIAnti-gensBCellResponsetoType2ofTIAnti-gensSection17BCellRecognitionandResp-onseofAntigensChapter3RulesofAntibodyProductionImmunoglobulinSecretionPrimaryandSecondaryResponseSection17BCellRecognitionandResp-onseofAntigensChapter4MucosalImmuneResponseMucosa-AssociatedLymphoidTissueSecretoryIgandTranscytosisSection18ImmunoregulationChapter1RoleofAntigen，AntibodyandComplementChapter2RoleofSignalingComponentsandMoleculesChapter3RoleofCellsChapter4NeuroendocrineImmuneSys-temRegulationSection18ImmunoregulationChapter1RoleofAntigen，AntibodyandComplementRoleofAntigenRoleofAntibodyRoleofComplementSection18ImmunoregulationChapter2RoleofSignalingComponentsandMoleculesRoleofActivatingSignalingComponentsandMoleculesRoleofSuppressingSignalingCompo-nentsandMoleculesChapter3RoleofCellsRoleofTCellSubtypesRoleoftheIdiotypicNetworkRoleofApoptosisSection18ImmunoregulationSection18ImmunoregulationChapter4NeuroendocrineImmuneSys-temRegulationRoleofNeuroendocrineSystemImmunoregulationAmongPopulationSection19ImmuneToleranceLOREMIPSUMLOREMIPSUMLOREMIPSUMChapter3ImmuneToleranceandClinicalMedicineEstablishmentandMaintenanceofIm-muneToleranceAbrogationofImmuneToleranceChapter2MechanismsofImmuneTole-ranceCentralTolerancePeripheralToleranceChapter1TheDevelopmentandRepre-sentationofImmuneToleranceInnateToleranceAcquiredToleranceCLINICALIMMUNOLOGYChapter1TypeIHypersensitivityChapter2TypeIIHypersensitivityChapter3TypeIIIHypersensitivityChapter4TypeIVHypersensitivitySection20HypersensitivityChapter1TypeIHypersensitivityComponentandCellsImmunePathogenesisTypeIHypersensitivity-AssociatedDiseasesTherapyforTypeIHypersensitivitySection20HypersensitivityChapter2TypeIIHypersensitivityImmunePathogenesisTypeIIHypersensitivity-AssociatedDiseasesSection20HypersensitivityChapter3TypeIIIHypersensitivityImmunePathogenesisTypeIIIHypersensitivity-AssociatedDiseasesSection20HypersensitivityChapter4TypeIVHypersensitivityImmunePathogenesisDiseasescausedbyDelayed-TypeHypersensitivitySection20HypersensitivitySection21AutoimmunityandAutoimmuneDiseasesChapter1IntroductionChapter2ImmunologicPathogenesisandTypicalDiseasesChapter3FactorsinDevelopmentofAutoimmuneChapter4TreatmentofAutoi

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