专业英语之黄芪丹参六味地黄丸

RadixAstragali〔黄芪〕MilkvetchRoot1第一页，共29页。OriginsTonicherbs滋补药材Heat-removingdrugs清热药Purgatingdrugs泻下药Medicinesforrheumatism祛风湿药Hemostatics止血药2第二页，共29页。PlantmorphologyAperennialherb,mainrootstout.多年生草本，主根粗壮。Stemerectandbranchedattheupperpart.茎直立，上局部枝。Leavesodd-pinnatelycompound,alternate.奇数羽状复叶，互生。Flowersinaxillaryracemes,calyxcampanulate.花为总状花序，腋生，花萼钟形。3第三页，共29页。CollectionandpreparationThedrugiscollectedinspringandautumn,removedfromsoil,rootletandrootstock,anddriedinsun.

春秋季节采收药材，去除泥土、细根、根头，晒干。4第四页，共29页。DescriptionExternallypalebrownish-yelloworpalebrown,withirregular,longitudinalwrinklesandmoretransverselenticel-likeprotrudings,corkeasilyexfoliated,exposingyellowish-whitecortex,sometimesshowingreticulatedfibrebundles.外表为浅棕黄色或浅棕色，有不规那么纵皱纹和众多横长皮孔样突起，栓皮易剥落而露出黄白色皮部，有时可见网状纤维束。Woodpaleyellowwithradiatestriationsandfissures,thecentrepartofoldrootoccasionallyrotten-wood-shaped.木部淡黄色，有放射状纹理和裂隙，老根中心偶呈枯朽状。5第五页，共29页。6第六页，共29页。理化鉴别Filter-filtrate过滤-滤液Neuralaluminiumoxidecolumn中性氧化铝rateElute-elutate洗脱-洗脱液Residue残渣n-butanolsaturatedwithwater水饱和正丁醇Thetestsolution供试品溶液CRSchemicalreferencestandards化学对照品Thereferencesolution标准溶液Thinlayerchromatography薄层色谱Sulfuricacid硫酸

formicacid甲酸Fluorescentspots荧光斑点7第七页，共29页。取本品粉末1g，加三氯甲烷20ml，加热回流30分钟，滤过，滤液蒸干，残渣加三氯甲烷1ml使溶解作为供试品溶液。另取五味子对照药材1g，同法制成对照药材溶液。再取五味子甲素对照品，加三氯甲烷制成每1ml含1mg的溶液，作为对照品溶液。8第八页，共29页。To1gofthepowderadd20mlofchloroform,heatunderrefluxonawaterbathfor0.5hour,filter,evaporatethefiltratetodryness.Dissolvetheresiduein1mlofchloroformasthetestsolution.ProduceasolutionofFructusSchsandraeChinensisreferencedruginthesamemannerasthereferencedrugsolution.Dissolvedeoxyschizandrin(五味子甲素)CRSinchloroformtoproduceasolutioncontaining1mgpermlasthereferencesolution.9第九页，共29页。照薄层色谱法〔附录VIB〕试验，吸取上述三种溶液各2uL，分别点于同一硅胶GF254薄层板上，以石油醚-甲酸乙酯-甲酸〔15：5：1〕的上层溶液为展开剂，展开，取出，晾干，置紫外灯光下检视。供试品色谱中，在与对照药材和对照品色谱相应的位置上，显相同颜色的斑点。10第十页，共29页。Carryoutthemethodforthinlayerchromatography(AppendixVIB),usingsilicagelGF254asthecoatingsubstanceandtheupperlayerofpetroleumether(30~60℃)-ethylformate-formicacid(15:5:1)asthemobilephase.Applyseparatelytotheplate2mleachofthethreesolutions.Afterdevelopingandremovaloftheplate,dryitinair,examineunderultravioletlight(254nm).Thespotsinthechromatogramobtainedwiththetestsolutioncorrespondinpositionandcolourtothespotsobtainedwiththereferencedrugsolutionandthereferencesolution.11第十一页，共29页。成效补气固表，排脓生肌适应症气虚乏力，久泻脱肛，自汗水肿，子宫脱垂，慢性肾炎蛋白尿，糖尿病，疮口久不愈合12第十二页，共29页。RadixetRhizomaSalviaeMiltiorrhizae

(丹参)13第十三页，共29页。PlantmorphologyDeciduous落叶的Pubescentadj.有软毛的Vermillionn.adj.朱红色的Serrateadj.锯齿的Verticillateadj.轮生的，环生的pseudo-假的Falcateadj.钩状的Retuseadj.〔树叶〕浅凹形的Apex顶点，尖端Anther花药，花粉囊Gynobasic雌蕊托14第十四页，共29页。Description/性状根茎呈圆柱形或圆锥形，常稍弯曲，有分支，长10-30cm，直径0．3-1.5cm。外表砖红色、棕红色或紫棕色。皮粗糙，有不规那么的纵沟或纵皱纹，老根外皮常呈鳞片剥落，根头部有时残留茎基。质坚而脆，易折断，断面不平坦，纤维性，外皮砖红色，本部导管成束，黄白色，呈放射状排列。气微，味甘微苦。15第十五页，共29页。Microscopicalcharacters显微特征Corkcellsyellowish-brown,subsquareorpolygonalinsurfaceview,containingreddish-crownpigments,dissolvedonmountinginchloralhydratesolution.木栓细胞黄棕色，外表观类方形或多角形，含有红棕色色素，水合氯醛透化后色素溶解。16第十六页，共29页。PhysicalandChemicalIdentificationApplyseveraldropsofthefiltratetoapieceoffilterpaper,allowittodryandexamineunderultra-violetlight,abrightbluish-greyfluorescenceisproduced.取几滴滤液于滤纸上，晾干，在紫外灯下检视，可见亮蓝灰色斑点。Exposethefilterpapertoammoniavapourfor20minutes,removethefilterpaperandexamineagainunderultravioletlight,apalebluish-greenfluorescentisproduced.将该滤纸至于氨蒸气中20min，取出，再在紫外灯下检视，可见浅蓝绿色荧光斑点。17第十七页，共29页。Ferricchloride三氯化铁Ether乙醚Astopperedtesttube具塞试管Ethylacetate乙酸乙酯Petroleumether石油醚Acetone丙酮Diluteethanol稀乙醇Absolutealcohol/anhydrousethanol无水乙醇18第十八页，共29页。AssayTanshinoneIIACarryoutthemethodforhighperformanceliquidchromatography(AppendixVID).ChromatographicsystemandsystemsuitabilityUseoctadecylsilanebondedsilicagelasthestationaryphaseandamixtureofmethanolandwater(75:25)asthemobilephase.Asdetectoraspectrophotometersetat270nm.Thenumberoftheoreticalplatesofthecolumnisnotlessthan2000,calculatedwiththereferencetothepeakoftanshinoneIIA.ReferencesolutionAccuratelyweigh10mgoftanshinoneIIACRStoa50mlambervolumbericflask.Dissolveanddilutewithmethanoltovolumeandmixwell.Accuratelymeasure2mltoa25mlvolumetricflask,dilutewithmethanoltovolume,andmixwell(containing16goftanshinoneIIAperml).19第十九页，共29页。TestsolutionWeightaccurately0.3gofthepowder(throughaNo.3sieve)toastopperconicalflask.Addaccurately50mlofmethanol,andweigh.Heatunderrefluxfor1hour,cool,weighagain,makeupthelossofweightwithmethanol,mixwellandfilter,usethesuccessivefiltrateasthetestsolution.20第二十页，共29页。ProcedureAccuratelyinject5lofeachofthereferencesolutionandthetestsolution,respectively,intothecolumn,determineandcalculatethecontent.Itcontainsnotlessthan0.2percentoftanshinoneIIA(C19H18O3).21第二十一页，共29页。ExtractivesWater-solubleextractivesCarryoutthemethodfordeterminationofwater-solubleextractives,notlessthan35.0percent.Ethanol-solubleextractives

Carryoutthemethodfordeterminationofethanol-solubleextractives(AppendixXA,hotextractionmethod),usingethanolasthesolvent,notlessthan15.0percent.

22第二十二页，共29页。ProcessingRemoveforeignmatterandremainsofstem,washclean,softenthoroughly,cutintothickslices,anddry.PrecautionIncompatiblewithVeratriNigriRadixetRhizoma(藜芦).Storage