Ulipristal-CDB-3236-DataSheet-生命科学试剂-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•Agonists•ScreeningLibrarieswww.MedChemEUlipristalCat.No.:HY-14959CASNo.:159811-51-5Synonyms:CDB-3236;DeacetylCDB-2914分⼦式:C₂₈H₃₅NO₃分⼦量:433.58作⽤靶点:ProgesteroneReceptor作⽤通路:Others储存⽅式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:≥250mg/mL(576.59mM)*"≥"meanssoluble,butsaturationunknown.MassSolvent1mg5mg10mgConcentration制备储备液1mM2.3064mL11.5319mL23.0638mL5mM0.4613mL2.3064mL4.6128mL10mM0.2306mL1.1532mL2.3064mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存⽅式和期限。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的⼯作液，建议您现⽤现配，当天使⽤；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分⽐指该溶剂在您配制终溶液中的体积占⽐)：1.请依序添加每种溶剂：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥6.25mg/mL(14.41mM);Clearsolution2.请依序添加每种溶剂：10%DMSO>>90%cornoilSolubility:≥6.25mg/mL(14.41mM);Clearsolution1/2MasterofSmallMolecules—您⾝边的抑制剂⼤师www.MedChemEBIOLOGICALACTIVITY⽣物活性Ulipristal(CDB3236)⼀种选择性的性孕酮受体(progesteronereceptor)调节剂。Ulipristal与孕激素受体结合，从⽽抑制PR介导的因表达，并⼲扰⽣殖系统中孕激素的活性。体内研究Ulipristal(CDB3236)maysuppressthegrowthofuterineleiomyomatosis.Byinhibitingordelayingovulationandeffectingendometrialtissue,ulipristalcanbeusedasanemergencycontraception[1].REFERENCES[1].LIANAPLES,etal.IsUlipristalAcetateaLiverToxicBiomolecule?Toxicityassessmentofulipristalacetate.REV.CHIM.(Bucharest).McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559