溶出研究进展周玉春学习教案

1、会计学1溶出研究进展周玉春溶出研究进展周玉春第一页，共78页。关于关于(guny) Distek(guny) Distek第1页/共78页第二页，共78页。一些重要一些重要(zhngyo)(zhngyo)的日期的日期第2页/共78页第三页，共78页。Distek Distek 产品产品(chnpn)(chnpn)UV-VisBench top (Agilent)Fiber Optics (UV only)溶媒制备验证服务IQ/OQ/PQ Services工具和配件Intrinsic 特性溶出Small Volume小体积(tj)溶出PatchesOintment Cells膏剂池Validat

2、ion Tools验证工具第3页/共78页第四页，共78页。原理原理(yunl)(yunl)第4页/共78页第五页，共78页。第5页/共78页第六页，共78页。第6页/共78页第七页，共78页。第7页/共78页第八页，共78页。第8页/共78页第九页，共78页。第9页/共78页第十页，共78页。第10页/共78页第十一页，共78页。第11页/共78页第十二页，共78页。第12页/共78页第十三页，共78页。第13页/共78页第十四页，共78页。4 position6 position7 position8 position100/200mL1L2L4LRequires addtl Spindl

3、e(s)第14页/共78页第十五页，共78页。Abbott LaboratoriesCadilia HealthcareIVC IndustriesPar Pharmaceuticals, Inc.Tahitian Noni InternationalABC LaboratoriesCapricorn Pharma, Inc.JFC TechnologiesPenniman & Browne, Inc.Taro PharmaceuticalsActavisCardinal HealthJubilant OrganosysPerrigo CompanyTechno ScaleAlphar

4、ma, USCeph International Corp.King Pharmaceuticals, Inc.Pfizer, Inc.Teva Pharmaceuticals, USAPharmaceuticals DivisionCephalon Inc.Laboratorio NeoPharmaceutical Associates, Inc.Texas Tech University HealthAnChen PharmaceuticalsCima LabsQuimca ComPharmafabSciences School of PharmacyAndrx PharmCobalt P

5、harmaceuticals Inc.LavipharmPharmagen, Inc.TPM Laboratories, Inc.Anmeal PharmaceuticalCorepharmaLaboratories, Inc.Pharma ScienceTransTech Pharma, Inc.CorporationDabur Research FoundationLehigh Valley Technologies, Inc.Pliva, Inc.United ResearchApotexDelavau LLCLohmann Therapy-SystemsPurdue Pharmaceu

6、ticals L.P.Laboratories/MutualArQule Inc.Dow Chemical CompanyMcNeil Consumer & Specialty PharmaceuticalsQuintiles Inc.Pharmaceutical CompanyAstraZeneca PharmaceuticalsDPT Laboratories, Ltd.MedPointe Consumer HealthcareRanbaxy LaboratoriesUnited States Food and Drug AdminAurobindo Pharma Ltd.Elan

7、 Pharmaceuticals, Inc.Medtronic, Inc.Roche Palo Alto LLCValeant Pharmaceuticals IntlBanner PharmacapsEon Labs, Inc.Mercer University SouthernRTI InternationalInternationalBarr LaboratoriesEthypharm, Inc.School of PharmacyRX ManufacturingVistakon, Inc. (Division ofBayer CorporationFrontage Laboratori

8、es, Inc.Merck & Company, Inc.Schering-Plough CorporationJohnson & Johnson)BioAnalytical Systems, Inc.GenpharmMerck Frosst Canada Ltd.Schwartz Pharma Inc.Watson LaboratoriesBiomarinGlaxoSmithKlineMission Pharmacal CompanyScientific GroupWell Spring PharmaceuticalPharmaceutical, Inc.Hercules,

9、Inc.Mova Pharmaceutical Corp.SGS U.S. Testing Company Inc.Wockhardt LimitedBiovail TechnologiesHikma PharmaceuticalsMylan PharmaceuticalsSicor Inc.Wyeth PharmaceuticalsBoehringer IngelheimImpax Laboratories, Inc.NutraSigmaPharm Laboratories, IncXenoPortPharmaceuticals, Inc.International Pharmaceutic

10、alsOrbus Pharma Inc.Sovereign Pharmaceuticals0ver 4000 unitsBristol-Myers SquibbInvaGen, Inc.Ortho-McNeil Pharmaceuticals, Inc.Synta Pharmaceuticals第15页/共78页第十六页，共78页。Essentials of Dissolution TestingEssentials of Dissolution Testing第16页/共78页第十七页，共78页。第17页/共78页第十八页，共78页。第18页/共78页第十九页，共78页。的特性有助于提高实验

11、室效率并提升可靠性。的特性有助于提高实验室效率并提升可靠性。第19页/共78页第二十页，共78页。第20页/共78页第二十一页，共78页。第21页/共78页第二十二页，共78页。第22页/共78页第二十三页，共78页。第23页/共78页第二十四页，共78页。第24页/共78页第二十五页，共78页。第25页/共78页第二十六页，共78页。第26页/共78页第二十七页，共78页。第27页/共78页第二十八页，共78页。第28页/共78页第二十九页，共78页。第29页/共78页第三十页，共78页。第30页/共78页第三十一页，共78页。第31页/共78页第三十二页，共78页。ABC Laborato

12、riesMatrix Laboratories LimitedPar Pharmaceuticals, Inc.ApotexMcNeil Consumer & SpecialtyRanbaxyBarr LaboratoriesPharmaceuticalsTeva Pharmaceuticals, USADabur Research FoundationMerck &United ResearchEssex Pharmaceuticals GmbhCompany, Inc.Laboratories/MutualForest Laboratories, Inc.Merckle G

13、mbhPharmaceutical CompanyHoffmann-LaRocheOhm Laboratories, Inc.Wyeth PharmaceuticalsInnovative HealthOrit LaboratoriesLannett Company, Inc.Paddock Laboratories, Inc.第32页/共78页第三十三页，共78页。ABC LaboratoriesImpax Laboratories, Inc.Pfizer, Inc.Teva Pharmaceuticals, USAAjinomotoIndustria QuimicaProcaps S.A.

14、ToriiAltrium S.A.FarmaceuticaProcter & GambleTyco Healthcare-ALZA CORPORATIONInternational Flavors & Fragrances, Inc.Produtos Roche Quim. E PharmaMallinckrodtArray Biopharma, Inc.Ivax PharmaceuticalsQuest Pharmaceuticals Services,LLCUniversity of Iowa College of PharmacyAutomated LabsJ.M. Hu

15、ber Engineered MaterialsRanbaxy LaboratoriesUPM PharmaceuticalsAvatar Pharmaceutical Services, Inc.Johnson & JohnsonRatiopharmValeant PharmaceuticalsBarr LaboratoriesKos Pharmaceuticals, Inc.Red River PharmaInternationalBen Venue LaboratoriesKosan Biosciences, Inc.Sandoz Pharmaceuticals.Victory

16、EnterprisesBrianfarma Industria QuimicaLabopharma, Inc.Sankyo PharmaWarnexBristol-Myers Squibb CompanyMerck & Company, Inc.Sanofi-AventisWatson LaboratoriesCardinal HealthMerckle GmbhSawaiWestward PharmaceuticalContract Pharmacal CorporationMidwest Research InstituteSchering-Plough CorporationCo

17、rporationDelavau LLCMillennium ScienceShire U.S. Manufacturing, Inc.Wyeth PharmaceuticalsDigestive Care, Inc.Morton Grove Pharmaceuticals, Inc.Sicor, Inc.Dr . R. Pfleger GmbhMutual Pharmaceutical CompanySt. Johns University School ofEisai, Inc.NovartisPharmacy and Allied HealthEli Lilly & Compan

18、yNovartis Vaccines & DiagnosticsProfessionsEssex Pharmaceuticals GmbhOSI Pharmaceuticals, Inc.Strides Acrolab, Ltd.GlaxoSmithKlineP3 Laboratories, LLCTaishoHi Tech Pharmacal Company Inc. Par Pharmaceuticals, Inc.TakedaHoffmann-LaRochePerrigo CompanyTeijin Pharma第33页/共78页第三十四页，共78页。6300第34页/共78页第

19、三十五页，共78页。6100第35页/共78页第三十六页，共78页。Evolution Basket vs. Knurled TypeEvolution Basket vs. Knurled Type第36页/共78页第三十七页，共78页。Evolution Basket Adapter vs. Knurled Type Evolution Basket Adapter vs. Knurled Type Basket AdapterBasket Adapter第37页/共78页第三十八页，共78页。第38页/共78页第三十九页，共78页。第39页/共78页第四十页，共78页。第40页/共78页

20、第四十一页，共78页。第41页/共78页第四十二页，共78页。第42页/共78页第四十三页，共78页。Syringe Filter AssemblySyringe Filter Assembly第43页/共78页第四十四页，共78页。第44页/共78页第四十五页，共78页。第45页/共78页第四十六页，共78页。第46页/共78页第四十七页，共78页。第47页/共78页第四十八页，共78页。第48页/共78页第四十九页，共78页。第49页/共78页第五十页，共78页。第50页/共78页第五十一页，共78页。第51页/共78页第五十二页，共78页。第52页/共78页第五十三页，共78页。第53页

21、/共78页第五十四页，共78页。第54页/共78页第五十五页，共78页。第55页/共78页第五十六页，共78页。第56页/共78页第五十七页，共78页。Evolution 4300 Users ListEvolution 4300 Users List第57页/共78页第五十八页，共78页。第58页/共78页第五十九页，共78页。第59页/共78页第六十页，共78页。第60页/共78页第六十一页，共78页。第61页/共78页第六十二页，共78页。第62页/共78页第六十三页，共78页。Bathless Tablet Disintegration Test SystemBathless Tabl

22、et Disintegration Test System第63页/共78页第六十四页，共78页。第64页/共78页第六十五页，共78页。Able to change to three positions第65页/共78页第六十六页，共78页。MD-1 Bench Top Media Degassing and Dispensing MD-1 Bench Top Media Degassing and Dispensing SystemSystem第66页/共78页第六十七页，共78页。-控制软件提供控制软件提供(tgng)最大灵活性最大灵活性第67页/共78页第六十八页，共78页。Two-stati