模拟失重大鼠肠系膜小动脉平滑肌细胞电压依赖性钙离子通道电流的_第1页
模拟失重大鼠肠系膜小动脉平滑肌细胞电压依赖性钙离子通道电流的_第2页
模拟失重大鼠肠系膜小动脉平滑肌细胞电压依赖性钙离子通道电流的_第3页
全文预览已结束

下载本文档

版权说明:本文档由用户提供并上传,收益归属内容提供方,若内容存在侵权,请进行举报或认领

文档简介

1、 32 生理学报 Acta Physiologica Sinica, February 25, 2005, 57(1: 27-32 10 2+ KV 上调 结合 L-VDC 的下调可使 Ca 内流减少, 这 可能也是失重下主要阻力性动脉血管功能与结构下 调的电生理学自体调节机制之一。但 L-VDC 电流密 度的降低是由于通道表达的降低还是单个通道功能 的改变引起还有待进一步阐明。 参考文献 1 Zhang LF ( 张立藩,Yu ZB, Ma J, Mao QW. Peripheral effector mechanism hypothesis on cardiovascular dysfun

2、ction after spaceflight. Prog Physiol Sci (生理科学进展 2001; 32(1:13-17 (Chinese, English abstract. 2 Buckey JC, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Moore WE, Gaffney FA, Blomqvist CG. Orthostatic intolerance after spaceflight. J Appl Physiol 1996; 81(1: 7-18. 3 Looft-Wilson RC,Gisolfi CV. Rat

3、small mesenteric artery function after hindlimb suspension. J Appl Physiol 2000; 88: 1199-1206. 4 Ma J, Zhang LN, Zhang LF. Vasoconstrictor responsiveness of hind body vascular beds is diminished in tail-suspended rats. J Gravit Physiol 2000; 7:153-154. 5 Delp MD, Colleran PN, Wilkerson MK, McCurdy

4、MR, Muller-Delp J. Structural and functional remodeling of skeletal muscle microvasculature is induced by simulated microgravity. Am J Physiol Heart Circ Physiol 2000; 278: 1866-1873. 6 Mao QW, Zhang LF, Ma J. Observation on arteriolar network structure in soleus of tail-suspended rats. J Gravit Phy

5、siol 1997; 4:129-130. 7 8 Zhang LF. Invited review: Vascular adaptation to microgravity: what have we learned? J Appl Physiol 2001; 91: 2415-2430. Somlyo AP, Somlyo AV. Signal transduction and regulation in smooth muscle. Nature 1994; 372: 231-236. 9 Jackson WF. Ion channels and vascular tone. Hyper

6、tension 2000; 35:173-178. 10 Fu ZJ (付兆君, Cheng HW, Zhang LF, Ma J. Changes in potassium currents of vascular smooth muscle cells isolated from hindquarter arteries of rats after 4 weeks simulated weightlessness. Acta Physiol Sin (生理学报 2002; 54: 525530 (Chinese, English abstract . 11 Morey-Holton ER,

7、Globus RK. Hindlimb unloading rodent model: technical aspects. J Appl Physiol 2002; 92:1367-1377. 12 He JQ (何加强, Qu JH, Zheng YF, Wang XF. Characteristics of voltage-dependent Ca2+ channels in smooth muscle cell membrane of visceral resistance vessel in SHRsp.Acta Biophys Sin (生物物理学报 1998; 14(3: 418

8、-427 (Chinese, English abstract. 13 Cox RH ,Rusch NJ . New expression profiles of voltagegated ion channels in arteries exposed to high blood pressure. Microcirculation 2002 ;9: 243-257. 14 Zhang LF, Zhang LN, Meng QJ, Fu ZJ. Research in differential adaptations of vessels to microgravity. 23rd Annu

9、al International Gravitational Physiology Meeting; 2002 June, Karolinska Institute, Sweden. ESA SP-501. J Gravit Physiol 2002; 9(1: P55-P58. 15 Yuan JX, Rubin LJ. Altered expression and function of Kv channels in primary pulmonary hypertension. In Archer and Rusch (eds. Potassium Channels in Cardiovascular Biology. New York: Kluwer Academic/ Plenum Publishers, 2001, 821836. 16 Fu ZJ, Xie MJ, Zhang LF, Cheng HW, Ma J. Differential activation of po

温馨提示

  • 1. 本站所有资源如无特殊说明,都需要本地电脑安装OFFICE2007和PDF阅读器。图纸软件为CAD,CAXA,PROE,UG,SolidWorks等.压缩文件请下载最新的WinRAR软件解压。
  • 2. 本站的文档不包含任何第三方提供的附件图纸等,如果需要附件,请联系上传者。文件的所有权益归上传用户所有。
  • 3. 本站RAR压缩包中若带图纸,网页内容里面会有图纸预览,若没有图纸预览就没有图纸。
  • 4. 未经权益所有人同意不得将文件中的内容挪作商业或盈利用途。
  • 5. 人人文库网仅提供信息存储空间,仅对用户上传内容的表现方式做保护处理,对用户上传分享的文档内容本身不做任何修改或编辑,并不能对任何下载内容负责。
  • 6. 下载文件中如有侵权或不适当内容,请与我们联系,我们立即纠正。
  • 7. 本站不保证下载资源的准确性、安全性和完整性, 同时也不承担用户因使用这些下载资源对自己和他人造成任何形式的伤害或损失。

评论

0/150

提交评论